ArticleBiology2025
Comparative Transcriptomics as a Key to Understanding the Adaptation Mechanisms of Baikal Sculpins to the Deep-Water Habitat.
Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Parallel Reduction in Skeletal Density During Benthic to Pelagic Transitions in Baikal Sculpins.Integrative organismal biology (Oxford, England) · 2026Article
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12 authors.
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Abstract
Understanding the molecular mechanisms that enable vertebrate adaptation to deep-water environments remains a central goal in evolutionary biology. This study used comparative transcriptomics of skeletal muscle tissue to investigate these mechanisms in four endemic sculpin fish species (Cottoidei) from Lake Baikal, which inhabit different depth niches ranging from pelagic to benthic-abyssal zones up to 1642 m. Pelagic species showed increased activity in genes involved in sarcomere structure, calcium handling, and motor proteins, indicating adaptations for sustained locomotion. In contrast, deep-benthic specialists showed enrichment in pathways for glycolytic metabolism, proteasome function, and ubiquitination, reflecting adaptations for energy efficiency and protein homeostasis in a high-pressure environment. We conclude that the colonization of the Baikal abyssal zone by sculpins relies on a suite of shared molecular mechanisms, with distinct ecological pressures driving specific transcriptional changes in motility, metabolic strategy, and cellular integrity. This study provides a systems-level model for deep-water adaptation in vertebrates.
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