Evidence map›Paper›PMID 41463342›Full record

ArticleBiomolecules2025

Assessment of [

Fariha Karim, Allyson Ngo, Titus E Tucker, Ashlee D L Coronel, Jogeshwar Mukherjee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Increased Binding of [Synapse (New York, N.Y.) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fariha KarimPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0009-0001-3104-9523
Allyson NgoPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0009-0002-6993-9131
Titus E TuckerPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0009-0009-6541-9842
Ashlee D L CoronelPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0009-0003-2810-766X
Jogeshwar MukherjeePreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0000-0003-1009-877X

Funding

Novel Tau-Targeted Radiohalogenated Agents for Alzheimer's DiseaseR01AG077700 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Jogeshwar Mukherjee · 2024 to 2026
$2.1M
Evaluation of Monoamine Oxidase-A as a New Biomarker for Alzheimer's DiseaseR21AG079189 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2022 to 2022
$432k
NIA NIH HHS R01 AG077700NIA NIH HHS R21 AG079189NIH HHS 3RF1AG029479-10NIH HHS 5R01AG077700-02
6 · The paper itself

Abstract

Parkinson's disease (PD) involves motor and cognitive impairment that nicotinic acetylcholine receptors (nAChRs) such as the α7 subtype are responsible for regulating. The hippocampus, abundant in α7 nAChRs, was quantitatively evaluated for [

Indexed as

alpha7 Nicotinic Acetylcholine ReceptorBungarotoxinsHippocampusParkinson DiseaseAgedAged, 80 and overalpha-SynucleinAlzheimer DiseaseFemaleHumansIodine RadioisotopesMaleMiddle AgedProtein Bindingalpha7 Nicotinic Acetylcholine Receptoralpha-SynucleinBungarotoxinsChrna7 protein, humanIodine-125Iodine Radioisotopes[125I]a-bungarotoxin[18F]ASEMLewy bodynicotinic acetylcholinergic receptorsParkinson’s diseaseubiquitinα-synuclein

Identifiers

PMID41463342
PMCPMC12731186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.