Evidence map›Paper›PMID 41463159›Full record

ArticleCancers2025

PROSTest, a Novel Liquid Biopsy Molecular Assay, Accurately Guides Prostate Cancer Biopsy Decision-Making in Men with Elevated PSA Irrespective of DRE Findings.

Craig G Rogers, Srinivas V Koduru, Anthony Gulati, Abdel B Halim

Registry-linked trialAbstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07454603 (A Single-arm, Multicenter Prospective Study to Evaluate the Diagnostic Performance of PROSTest in Men With PSA ≥ 3ng/ml Using Biopsy as the Sole Ground Truth), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07454603 recruitingnot on this mapstarted 2026, after this paper: background citation

A Single-arm, Multicenter Prospective Study to Evaluate the Diagnostic Performance of PROSTest in Men With PSA ≥ 3ng/ml Using Biopsy as the Sole Ground Truth

TypeobservationalSponsorWren Laboratories LLCRan2026 to 2027Enrolled1,500ConditionsProstate Cancer, Urology, Prostate Cancer (Diagnosis)ArmsPROSTEST
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Craig G RogersVattikuti Urology Institute, Henry Ford Health, Detroit, MI 48202, USA.
Srinivas V KoduruWren Laboratories, Branford, CT 06405, USA.ORCID 0000-0001-6827-2908
Anthony GulatiBennett Cancer Center, Stamford, CT 06902, USA.
Abdel B HalimWren Laboratories, Branford, CT 06405, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biopsyDREprostate cancerPROSTestPSAstratification

Identifiers

PMID41463159
PMCPMC12730410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.