Evidence map›Paper›PMID 41462838›Full record

ArticleChildren (Basel, Switzerland)2025

Risk Factors and Clinical Outcomes of Post-Extubation Stridor in Pediatric Intensive Care.

Jakeline Godinho Fonseca, Cristiane Fernandes de Moura, Geovana Soffa Rézio, Laís Aparecida da Silva, Mayara Moreira de Deus, Amanda Elis Rodrigues, Juliana Alves de Sousa Caixeta, Luiza Avelino Ferri, Melissa Ameloti Gomes Avelino

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jakeline Godinho FonsecaPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia 74690-900, Brazil.
Cristiane Fernandes de MouraPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia 74690-900, Brazil.
Geovana Soffa RézioPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia 74690-900, Brazil.
Laís Aparecida da SilvaHospital Estadual de Urgências Governador Otávio Lage de Siqueira (HUGOL), Goiânia 74463-350, Brazil.
Mayara Moreira de DeusPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia 74690-900, Brazil.
Amanda Elis RodriguesPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia 74690-900, Brazil.
Juliana Alves de Sousa CaixetaPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia 74690-900, Brazil.ORCID 0000-0002-0731-3224
Luiza Avelino FerriFaculdade de Medicina, Faculdade Ciências Médicas da Santa Casa de São Paulo, (FCMSCSP), São Paulo 01224-001, Brazil.
Melissa Ameloti Gomes AvelinoPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás (UFG), Goiânia 74690-900, Brazil.ORCID 0000-0003-0342-0978

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess risk factors for post-extubation stridor in children and its impact on clinical outcomes.

methodsProspective cohort study with children aged from 0 to 13 years who were intubated or underwent orotracheal intubation in the pediatric intensive care units (PICU) of two tertiary public hospitals. The outcome of interest was the occurrence of post-extubation stridor. The information collected included patient characteristics, comorbidities, history of airway manipulation, and factors related to orotracheal intubation. A logistic regression was used to identify potential risk factors for post-extubation stridor; data were analyzed until hospital discharge, death, or referral to another facility.

resultsA total of 239 children were included, with a median age of 1.3 years and a duration of intubation of three days. Post-extubation stridor was observed in 57.3% of children. A multivariate analysis included prehospital or non-specialized hospital intubation, trauma or complications during intubation, and orotracheal intubation longer than seven days as risk factors for stridor. Children with stridor had a longer PICU length of stay, longer duration of invasive mechanical ventilation, and were often managed with non-invasive ventilation (

conclusionsRisk factors for post-extubation stridor included intubation performed in prehospital or non-specialized hospitals, orotracheal intubation longer than seven days, and trauma or complications during intubation. Children with stridor had a worse prognosis, with longer stays in the PICU and on mechanical ventilation and higher rates of extubation failure.

Indexed as

airway extubationmechanical ventilationpediatric intensive care unitrespiratory sounds

Identifiers

PMID41462838
PMCPMC12731651

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.