ArticleChildren (Basel, Switzerland)2025
Comparing Surgical Stress in Children Undergoing Open and Laparoscopic Inguinal Hernioplasty-A Single Center's Prospective Study Results.
Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
backgroundInguinal hernioplasty in the pediatric population is a common minor injury operation. Whether the surgical approach alters perioperative stress responses remains uncertain. The aim of this study was to compare early inflammatory and endocrine stress markers after open (OIH) and laparoscopic inguinal hernioplasty (LIH).
methodsA single-center prospective observational study with 1:1 allocation between 2021 and 2023. Otherwise healthy children, scheduled for elective unilateral indirect inguinal hernia repair, were assigned to open or laparoscopic hernioplasty. Blood samples were collected at five time points, measuring levels of white blood cells, cortisol, MDA, ferritin, albumin, and CRP. Analyses used two-way repeated measures ANOVA with Greenhouse-Geisser correction and Bonferroni-adjusted planned contrasts at 24 h.
resultsThirty-two children aged from 2.4 months to 11 years with a mean age of 3.8 years (± 2.46 Standard Deviation, SD) were randomized equally. Operative times were longer in the laparoscopic group [01:07 (±00:20-SD)]; [open group operative duration: 00:41 (±00:16-SD), (
conclusionsThis study demonstrates that LIH and OIH in children have a comparable impact on the inflammatory response. LIH is a safe and effective alternative to the traditional open repair method regarding operative stress. To validate these findings and assess the long-term implications of each surgical approach on children's pathophysiology, further research is warranted.
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