Evidence map›Paper›PMID 41462649›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Cuspidatyl Ferulate, a Novel Phenolic Acid from

Xingyu Liu, Zhao Zhang, Denghui Gao, Xiaoguang Yang, Lei Liu, Guannan Wang, Zhenbo Song, Weiwei Fang, Shuyue Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xingyu LiuNational Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130117, China.ORCID 0000-0002-9661-5995
Zhao ZhangNational Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130117, China.
Denghui GaoNMPA Key Laboratory for Quality Control of Cell and Gene Therapy Medicine Products, Northeast Normal University, Changchun 130032, China.ORCID 0000-0002-5291-4117
Xiaoguang YangNMPA Key Laboratory for Quality Control of Cell and Gene Therapy Medicine Products, Northeast Normal University, Changchun 130032, China.
Lei LiuSchool of Life Sciences, Northeast Normal University, Changchun 130032, China.
Guannan WangSchool of Life Sciences, Northeast Normal University, Changchun 130032, China.
Zhenbo SongNational Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130117, China.
Weiwei FangDepartment of Blood Transfusion, State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Shuyue WangNational Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun 130117, China.ORCID 0000-0002-0048-7264

Funding

Beijing Natural Science Foundation 7242120Jilin Provincial Science & Technology Development YDZJ202201ZYTS439
6 · The paper itself

Abstract

Lipotoxicity and oxidative stress are key pathogenic drivers in the development of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). The underlying mechanisms of MASLD are not fully understood, and approved pharmacotherapies remain elusive. Thus, exploring therapeutic targets and potential drugs for MASLD is still a major challenge. In our previous study, a new cuspidatyl ferulate (2,3-dihydroxy-4-carboxylic butyl (E)-4-[3-(4-hydroxy-3-methoxyphenyl)-2-propenoate], CuF) was first isolated and identified from

Indexed as

antioxidantHyssopus cuspidatus BorrisKeap1-Nrf2 pathwaylipotoxicityMASLDoxidative stressphenolic acid

Identifiers

PMID41462649
PMCPMC12729638

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.