Evidence map›Paper›PMID 41462622›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Linoleic Hydroperoxides Are Potent Hyperoxidative Agents of Sensitive and Robust Typical 2-Cys Peroxiredoxins.

Vitória Isabela Montanhero Cabrera, Sabrina Vargas, Nathália Miranda de Medeiros, Gabrielle Nascimento Sividanes, Laura Fernandes da Silva, Larissa Regina Diniz, Thiago Geronimo Pires Alegria, João Henrique Ghilardi Lago, Marcos Hikari Toyama, Sayuri Miyamoto and 3 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Vitória Isabela Montanhero CabreraInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 11330-900, SP, Brazil.ORCID 0000-0002-7271-9626
Sabrina VargasInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 11330-900, SP, Brazil.ORCID 0000-0003-2489-7003
Nathália Miranda de MedeirosDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-2998-3480
Gabrielle Nascimento SividanesInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 11330-900, SP, Brazil.ORCID 0009-0004-3506-5573
Laura Fernandes da SilvaInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 11330-900, SP, Brazil.ORCID 0009-0007-3966-2350
Larissa Regina DinizDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.ORCID 0000-0001-9259-507X
Thiago Geronimo Pires AlegriaDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo 05508-090, SP, Brazil.ORCID 0000-0002-3086-4059
João Henrique Ghilardi LagoCentro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André 09210-180, SP, Brazil.ORCID 0000-0002-1193-8374
Marcos Hikari ToyamaInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 11330-900, SP, Brazil.ORCID 0000-0001-6836-3084
Sayuri MiyamotoDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-5714-8984
Daniela Ramos TruzziDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.ORCID 0000-0003-4421-9621
Luis Eduardo Soares NettoDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo 05508-090, SP, Brazil.ORCID 0000-0002-4250-9177
Marcos Antonio de OliveiraInstituto de Biociências, Universidade Estadual Paulista, UNESP, São Vicente 11330-900, SP, Brazil.ORCID 0000-0002-1192-7296

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/07937-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/19942-7Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/20291-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/17483-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/11225-0/FellowshipFundação de Amparo à Pesquisa do Estado de São Paulo 2023/01263-7/FellowshipFundação de Amparo à Pesquisa do Estado de São Paulo 2023/12447-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/18481-7/FellowshipFundação de Amparo à Pesquisa do Estado de São Paulo 2025/01281-0/FellowshipNational Council for Scientific and Technological Development 309271/2022-3National Council for Scientific and Technological Development 313926/2021-2National Council for Scientific and Technological Development 421934/2023-9National Council for Scientific and Technological Development 442831/2023-4
6 · The paper itself

Abstract

Typical 2-Cys peroxiredoxins (2-Cys Prxs, AhpC/Prx1 subfamily) are ubiquitous thiol peroxidases that efficiently reduce H

Indexed as

enzyme inhibitionhyperoxidationlong chain fatty acids hydroperoxidesperoxiredoxin

Identifiers

PMID41462622
PMCPMC12729873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.