Observational studyScientific reports2025
Six-month clinical outcomes after ST-elevation myocardial infarction in eastern Indonesia: a prospective cohort study.
Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Impact of nursing strategy based on the 6S management model on clinical outcomes in patients with acute myocardial infarction after Percutaneous Coronary intervention.Pakistan journal of medical sciences · 2026Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate the six-month major adverse cardiovascular and cerebrovascular events (MACCE) among ST-elevation myocardial infarction (STEMI) patients, and identify their predictors. This single-centre, prospective observational study involved STEMI patients who presented to the Makassar Cardiac Centre in Indonesia from July 2018 to June 2020. Consecutive sampling was employed. The primary endpoint was MACCE (including all-cause mortality, heart failure requiring hospitalization, reinfarction, and stroke) during hospitalization, at 30-day and 6-month follow-up. We recruited 365 patients with a mean age of 57.1 ± 10.3 years, and predominantly male (n = 294, 80.5%). Majority of the patients (n = 206, 56.4%) received reperfusion therapy, with 104 (28.5%) underwent primary percutaneous coronary intervention (PPCI) and 102 (27.9%) received fibrinolysis. Six-month mortality was higher without reperfusion than with PPCI or fibrinolysis (26.4% vs 17.3% vs 13.7%, p = 0.030). MACCE occurred in 23.6% at 30 days and 57.0% at 6 months. Most STEMI patients in East Indonesia were latecomers, with a median time from onset to hospitalization of 350 min. Independent predictors of 6-month MACCE were age ≥ 60 years (HR 1.45, p = 0.032), Killip class ≥ 2 (HR 2.06, p < 0.001), anterior MI (HR 1.47, p = 0.024), renal impairment (HR 1.57, p = 0.015), medication non-adherence (HR 1.70, p = 0.001), and hospital stay ≥ 8 days (HR 1.48, p = 0.018). The high incidence of MACCE at 6 months following STEMI in our region is worrisome. Identified MACCE predictors can guide better STEMI management. To reduce MACCE following STEMI, it is crucial to raise symptom awareness, expedite PPCI activation, and strengthen hospital infrastructure and resources for STEMI care.
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