Observational studyBMC women's health2025
Is exercise duration more important than intensity in endometriosis?
Observational study in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExercise may be a useful adjunct treatment strategy to manage symptom severity and improve quality of life of women with endometriosis. This cross-sectional observational study aimed to investigate the associations between exercise habits, systemic biomarkers, quality of life and mental health in women with endometriosis.
methodsExercise habits, health related quality of life (via the endometriosis health profile (EHP-30)), adiposity and salivary measures of c-reactive protein (CRP), cortisol, and estradiol were collected from 21 women with endometriosis and compared to a control group (n = 13; women without endometriosis). Self-reported exercise habits and health-related quality of life were collected via an online survey. Saliva was self-collected via passive drool on day 12 of the menstrual cycle (within 45-60 min of waking) and analysed for biomarkers. Body composition was assessed via dual-energy x-ray absorptiometry.
resultsAn inverse relationship between minutes completed per individual exercise session and levels of CRP, estradiol, android and gynoid fat mass, and pain associated with endometriosis were observed in women with endometriosis (p < 0·05). There were no significant relationships between total volume, metabolic equivalent of task (MET) minutes or vigorous MET minutes in women with endometriosis (p > 0·05). Levels of CRP were positively correlated with gynoid fat mass, whereas higher levels of pain were positively associated with android fat mass(p < 0·05). Furthermore android fat mass was positively correlated with poor self-image and lower levels of control and increased powerlessness (p < 0·05).
conclusionsThe inverse relationship between the duration of individual exercise sessions and CRP, estradiol, pain and fat distribution is a novel finding, suggesting that longer durations of acute bouts of exercise, regardless of intensity and total volume, are associated with improvements in biological and psychological variables in women with endometriosis.
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