ArticleBiological research2025
Influence of pigment epithelium-derived factors on H
Article in Biological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Source-Dependent Mitochondrial Transplantation Drives Schwann Cell Bioenergetic Reprogramming and Peripheral Nerve Regeneration.Advanced healthcare materials · 2026Article
- Sedative effects of physcion and its modulatory interaction with diazepam: in vivo and in silico evaluation.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Gypenoside XLIX and Mitochondria-Associated ER Membranes in Non-Alcoholic Fatty Liver Disease: Mechanistic Insights and Emerging Perspectives.Molecules (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundPrevious studies have demonstrated that oxidative stress and melanogenesis are regulated by the Wnt/β-catenin signaling pathway. However, the precise mechanism by which the PEDF/Wnt/β-catenin axis modulates apoptosis and melanogenesis remains unclear.
methodsCell viability and mortality rates were assessed using CCK-8 assays and lactate dehydrogenase (LDH) release assays. Mitochondrial ultrastructural changes were analyzed by transmission electron microscopy (TEM). Changes in the mitochondrial membrane potential (ΔΨm) were assessed using the JC-1 fluorescent probe. The effects of PEDF on protein and gene expression were evaluated by Western blotting and quantitative real-time polymerase chain reaction (qRT-PCR).
resultsAs the concentration of H
conclusionsThese results suggest that PEDF can reduce H
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.