Evidence map›Paper›PMID 41462271›Full record

ArticleVirology journal2025

Genetic evolution of Akabane virus isolates and the protective efficacy of inactivated vaccines.

Peng Wang, Mingzhu Zhang, Yanxin Qi, Xinyu Cao, Weixin Ji, Xiao Li, Zirui Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peng WangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No.573, Yujinxiang Street, Jingyue District, Changchun, 130122, China.
Mingzhu ZhangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No.573, Yujinxiang Street, Jingyue District, Changchun, 130122, China.
Yanxin QiFaculty of Chemistry, Northeast Normal University, Changchun, China.
Xinyu CaoChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No.573, Yujinxiang Street, Jingyue District, Changchun, 130122, China.
Weixin JiChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No.573, Yujinxiang Street, Jingyue District, Changchun, 130122, China.
Xiao LiChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No.573, Yujinxiang Street, Jingyue District, Changchun, 130122, China. skylee6226@163.com.
Zirui LiuChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No.573, Yujinxiang Street, Jingyue District, Changchun, 130122, China. killmarsking@163.com.

Funding

Jilin Province Science and Technology Development Plan Item YDZJ202203CGZH052
6 · The paper itself

Abstract

Akabane virus infection can cause abortion, stillbirth in pregnant ruminants, and congenital malformations in newborns. It is prevalent in most regions of Asia, as well as parts of Africa and Europe, causing severe impacts on the livestock industry. Inactivated vaccines are one of the effective means of disease prevention. In this study, an AKAV strain (CH-JL-01-2022) belonging to genetic group I was isolated, and based on this strain, an inactivated vaccine was developed, with screening conducted for the inactivating agent and adjuvant. Formaldehyde can completely inactivate AKAV, and mixed with the Imject

Indexed as

Bunyaviridae InfectionsEvolution, MolecularOrthobunyavirusViral VaccinesAdjuvants, ImmunologicAdjuvants, VaccineAlum CompoundsAnimalsAntibodies, NeutralizingAntibodies, ViralCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesFemaleFormaldehydeVaccine EfficacyVaccines, InactivatedAdjuvants, ImmunologicAdjuvants, VaccineAlum Compoundsaluminum sulfateAntibodies, NeutralizingAntibodies, ViralFormaldehydeVaccines, InactivatedViral VaccinesAdjuvantsAkabane virusImmunogenicity evaluationInactivated vaccines

Identifiers

PMID41462271
PMCPMC12750954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.