ReviewBMC infectious diseases2025
Subacute prosthetic aortic endocarditis caused by Actinotignum schaalii: a rare but destructive pathogen - case report and literature review.
Review in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundActinotignum schaalii is an emerging urogenital pathogen rarely reported as a cause of endocarditis. CASE PRESENTATION: A 54-year-old man developed recurrent embolic strokes seven and eight years post-Bentall procedure with mechanical aortic valve. Blood cultures grew Gram-positive bacilli, initially misidentified as Corynebacterium spp., later confirmed as Actinotignum schaalii. Cardiac CT revealed a 12 mm × 15 mm × 20 mm perivalvular abscess fistulizing into the sinus of Valsalva and prosthetic graft. 18 F-FDG PET/CT confirmed intense hypermetabolism around the prosthesis. Despite targeted amoxicillin therapy, intraoperative exploration revealed complete Bentall conduit dehiscence from extensive aorto-mitral trigone destruction. Reconstruction was deemed unfeasible, and the patient died following multidisciplinary decision to limit interventions. No urological source was identified.
conclusionsActinotignum schaalii can cause indolent prosthetic valve endocarditis with devastating perivalvular complications. Prolonged blood culture incubation is crucial for early diagnosis in patients with prosthetic material and unexplained embolic events. CLINICAL TRIAL: Not applicable.
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