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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Gender differences in the relationship between alcohol use patterns and health-related quality of life in a population experiencing a recent surge in harmful alcohol use among females: the 2018 National survey in Taiwan.

Tzu-Yu Chen, Shang-Chi Wu, Shu-Sen Chang, Lian-Yu Chen, Po-Hsiu Kuo, Chuan-Yu Chen, Hsiang-Wen Lin, Po-Chang Hsiao, Te-Tien Ting, Cheng-Fang Yen and 5 more

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Tzu-Yu ChenInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei, 100, Taiwan.
Shang-Chi WuInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei, 100, Taiwan.
Shu-Sen ChangDepartment of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan.
Lian-Yu ChenNational Health Insurance Administration, Ministry and Health and Welfare, Taipei, Taiwan.
Po-Hsiu KuoInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei, 100, Taiwan.
Chuan-Yu ChenInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei, 100, Taiwan.
Hsiang-Wen LinSchool of Pharmacy and Graduate Institute, College of Pharmacy, China Medical University, Taichung, Taiwan.
Po-Chang HsiaoInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei, 100, Taiwan.
Te-Tien TingSchool of Big Data Management, Soochow University, Taipei, Taiwan.
Cheng-Fang YenDepartment of Psychiatry, Kaohsiung Medical University Hospital & School of Medicine and Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chung-Yi LiDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Hao-Jan YangDepartment of Public Health, College of Health Care and Management, Chung Shan Medical University, Taichung, Taiwan.
Chia-Feng YenDepartment of Public Health, College of Medicine, Tzu Chi University, Hualien, Taiwan.
Yu-Kang TuInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei, 100, Taiwan.
Wei J ChenInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei, 100, Taiwan. wjchen@nhri.edu.tw.ORCID http://orcid.org/0000-0001-5899-5870

Funding

FDA HHS 107TFDA-N-001, and 110TFDA-N-002Ministry of Science and Technology, Taiwan MOST 106-2314-B-532-010-MY2
6 · The paper itself

Abstract

purposeWe aimed to investigate whether alcohol use patterns are linked to different components of health-related quality of life (HRQoL) and whether gender moderates these relationships in a population experiencing a recent surge in harmful alcohol use among females.

methodsParticipants included 15,028 adults aged 18–64 years from the 2018 National Survey of Substance Use in Taiwan. Alcohol use was assessed using the Alcohol Use Disorders Identification Test (AUDIT), and HRQoL was measured using the EQ-5D-5 L. Participants were classified as abstainers, former drinkers (AUDIT 0), low-risk drinkers (AUDIT 1–7), or harmful drinkers (AUDIT ≥ 8). EQ-5D-5 L dimensions were dichotomized, while the EQ VAS and index scores were used as continuous variables. Multivariable logistic and linear regressions were conducted to assess the associations between alcohol use patterns and HRQoL after adjusting for sociodemographic and clinical covariates.

resultsThe weighted prevalence was 46.22% for abstainers, 7.95% for former drinkers, 39.62% for low-risk drinkers, and 6.21% for harmful drinkers. Compared with abstainers, only low-risk drinkers were associated with limited beneficial effects in terms of decreased odds of problems with mobility and usual activities. However, all former, low-risk, and harmful drinkers were consistently associated with higher odds of experiencing pain/discomfort and anxiety/depression. The latter was moderated by gender, with female drinkers having significantly greater odds than males.

conclusionsAlcohol consumption has a multifaceted relationship with HRQoL, but all patterns of alcohol use are associated with poorer HRQoL in the pain/discomfort and anxiety/depression dimensions, with females being more vulnerable to anxiety/depression than males.

Indexed as

Alcohol DrinkingAlcoholismQuality of LifeAdolescentAdultDepressionFemaleHealth SurveysHumansMaleMiddle AgedPrevalenceSex FactorsSurveys and QuestionnairesTaiwanYoung AdultAlcohol useAnxietyDepressionEQ-5D-5LGender differencesHealth-related quality of life

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.