ReviewCurrent microbiology2025
Natural Anti-Biofilm Agents: A Comprehensive Review and Future Perspectives.
Review in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Synthesis, Antibacterial Evaluation, and Chemometric Profiling of a Vanilloid-Based Compounds Library Active AgainstAntibiotics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms, complex microbial communities embedded in extracellular polymeric substances (EPS), pose significant challenges across medical, industrial and environmental sectors due to their enhanced resistance to antibiotics and chemical agents. Traditional treatments often fail to combat biofilm-associated infections, leading to increased healthcare costs and mortality rates. This comprehensive review explores the potential of natural anti-biofilm agents derived from plants, microorganisms, marine organisms and other natural sources as alternative strategies. Plant-derived compounds, microbial products and marine bioactive substances exhibit promising anti-biofilm properties through various mechanisms, including inhibition of microbial adhesion, quorum sensing (QS) interference and EPS disruption. The review highlights the efficacy of these agents in both in vitro and in vivo studies and discusses their potential applications in industries such as medicine, food processing and water treatment. Despite the promising results, challenges such as standardization, biocompatibility and environmental impact remain. Future research should focus on optimizing these natural agents and exploring synergistic combinations to enhance their efficacy. This review underscores the importance of sustainable and interdisciplinary approaches in developing effective, eco-friendly anti-biofilm strategies for diverse applications.
Indexed as
Identifiers
41461973What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.