ArticleNature neuroscience2026
Charting brain morphology in international healthy and neurological populations.
Abstract read
In one paragraph
Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Motivation and pleasure deficits reflect altered network embedding of normal brain deviations in schizophrenia.Schizophrenia research · 2026Article
- Integrative gene target mapping, RNA sequencing, in silico molecular docking, ADMET profiling and molecular dynamics simulation study of marine derived molecules for type 1 diabetes mellitus.Molecular diversity · 2026Article
- Longitudinal Spinal Cord Atrophy in Patients With Neuromyelitis Optica Spectrum Disorder and Its Association With Rituximab Treatment.Neurology · 2026Article
- Article
- Molecules of mood: the integrated molecular transducers of exercise's antidepressant effects.Molecular genetics and genomics : MGG · 2026Review
- NeuroFM: Toward Precision Neuroimaging with Foundation Models for Individualized Brain Health Estimation.medRxiv : the preprint server for health sciences · 2026Article
- Unified Multi-Cohort Harmonisation and Normative Modelling of Neuroimaging Data via Hierarchical GAMLSS.bioRxiv : the preprint server for biology · 2026Article
- Article
- Oral microbiota dysbiosis related to the cortical thinning and cognitive impairment in cerebral small vessel disease.Journal of oral microbiology · 2026Article
- [Advances in the application of individualized white-matter functional networks in children and adolescents with attention-deficit/hyperactivity disorder].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsReview
- Functional connectome signature of general psychopathology in middle-aged and older adults: Evidence from multi-cohort, multi-ethnic analyses.Imaging neuroscience (Cambridge, Mass.)Article
- Individualized cholinergic pathway degeneration in Alzheimer's disease characterized by normative modeling.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
124 authors.
Zhizheng Zhuo *Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0002-6635-8705
Li Chai *Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yinshan Wang *State Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, Beijing, China.
Peng Gao *State Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, Beijing, China.ORCID http://orcid.org/0000-0002-7908-6075
Xiaolu Xu *Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Liping AiDepartment of Radiology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Feng AoDepartment of Radiology, Renmin Hospital, Hubei University of Medicine, Shiyan, China.
Yalin BaiDepartment of Radiology, Yuci Renmin Hospital, Jinzhong, China.
Yutong BaiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
James H ColeCentre for Medical Image Computing, University College London, London, UK.
Haihua BaoDepartment of Medical Imaging Center, Qinghai University Affiliated Hospital, Xining, China.
Qing CaiSchool of Psychology and Cognitive Science, East China Normal University, Shanghai, China.ORCID http://orcid.org/0000-0002-8341-3833
Jiancang CaoDepartment of Radiology, Gansu Provincial Hospital, Lanzhou, China.
Feiyan ChenSchool of Physics, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0003-3730-1651
Feng ChenDepartment of Radiology, Hainan General Hospital, Haikou, China.ORCID http://orcid.org/0000-0002-9129-7895
Kun ChenCentre for Cognitive and Brain Sciences and Department of Psychology, University of Macau, Macau, China.ORCID http://orcid.org/0000-0002-9138-3195
Yaojing ChenState Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, Beijing, China.
Dan ChengDepartment of Radiology, University of Washington School of Medicine, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0555-3275
Zaixu CuiChinese Institute for Brain Research, Beijing, China.ORCID http://orcid.org/0000-0003-4385-8106
Hui DaiDepartment of Radiology, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Demao DengDepartment of Radiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Yuhui DuSchool of Computer and Information Technology, Shanxi University, Taiyuan, China.ORCID http://orcid.org/0000-0002-0079-8177
Guoguang FanDepartment of Radiology, The First Hospital of China Medical University, Shenyang, China.
Ying FuDepartment of Neurology and Institute of Neurology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Zheqi GaoDepartment of Radiology, Yuci Renmin Hospital, Jinzhong, China.
Lubin GouDepartment of Radiology, Lanzhou University First Affiliated Hospital, Lanzhou, China.
Chunjie GuoDepartment of Radiology, The First Hospital of Jilin University, Changchun, China.
Min GuoDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0002-2291-1230
Ya GuoDepartment of Medical Imaging Center, Qinghai University Affiliated Hospital, Xining, China.
Xuemei HanDepartment of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Hongjian HeSchool of Physics, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0001-6272-0810
Yang HouDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang, China.
Basheng HuDepartment of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jianping HuDepartment of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Chu-Chung HuangSchool of Psychology and Cognitive Science, East China Normal University, Shanghai, China.ORCID http://orcid.org/0000-0002-9096-9610
Peiyu HuangDepartment of Radiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Junqiang LeiDepartment of Radiology, Lanzhou University First Affiliated Hospital, Lanzhou, China.
Hui-Jie LiState Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Jianrui LiDepartment of Diagnostic Radiology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Junlin LiDepartment of Imaging Medicine, Inner Mongolia Autonomous Region People's Hospital, Hohhot, China.
Kexuan LiDepartment of Radiology, Zhejiang Province People's Hospital, Hangzhou, China.
Shaowu LiBeijing Neurosurgical Institute, Beijing, China.
Wenling LiDepartment of Radiology, General Hospital of Ningxia Medical University, Yinchuan, China.
Xinyu LiDepartment of Imaging, Shanxi Provincial People's Hospital, Taiyuan, China.
Yang LiChinese Institute for Brain Research, Beijing, China.
Yao LiNational Engineering Research Center of Advanced Magnetic Resonance Technologies for Diagnosis and Therapy, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.ORCID http://orcid.org/0000-0001-5009-7443
Yongmei LiDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yuna LiDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yunfei LiDepartment of Radiology, The Fifth People's Hospital of Shanghai Fudan University, Shanghai, China.
Peipeng LiangSchool of Psychology, Capital Normal University, Beijing, China.
Haiyan LiaoDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Ching-Po LinInstitute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-6848-8776
Jun LiuDepartment of Radiology, Chongqing University Central Hospital, Chongqing, China.
Jungang LiuDepartment of Radiology, Xiamen Children's Hospital (Children's Hospital of Fudan University at Xiamen), Xiamen, China.
Weiqi LiuSophmind Technology (Beijing), Beijing, China.ORCID http://orcid.org/0009-0002-6221-7136
Ying LiuDepartment of Radiology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, China.
Shanshan LuDepartment of Radiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Jie LuoNational Engineering Research Center of Advanced Magnetic Resonance Technologies for Diagnosis and Therapy, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Yuqi LuoDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0003-2086-5645
Su LuiHuaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, China.ORCID http://orcid.org/0000-0003-3541-1769
Hailin MaTibet Autonomous Region Key Laboratory for High Altitude Brain Science and Environmental Acclimatization, Lhasa, China.
Ning MaoDepartment of Radiology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Lanxi MengBeijing Neurosurgical Institute, Beijing, China.
Linghui MengDepartment of Radiology, Hebei Medical University Third Hospital, Shijiazhuang, China.
Yinfeng QianDepartment of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Jun QiuDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Mengjie RongState Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, Beijing, China.ORCID http://orcid.org/0009-0007-2682-5886
Juwei ShaoThe Affiliated Hospital of Yunnan University, Kunming, China.
Qin ShenDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Yulu ShiDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhenyu ShuDepartment of Radiology, Zhejiang Province People's Hospital, Hangzhou, China.
Jun SunDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Decai TianDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yiheng TuState Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Fei WangDepartment of Radiology, Hainan General Hospital, Haikou, China.
Jinhui WangInstitute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, China.
Junkai WangDepartment of Radiology, Aerospace Center Hospital, Beijing, China.
Wen WangDepartment of Radiology and Functional and Molecular Imaging Key Lab of Shaanxi Province, Fourth Military Medical University, Xi'an, China.ORCID http://orcid.org/0000-0001-6473-4888
Xiaochun WangDepartment of Radiology, First Hospital of Shanxi Medical University, Taiyuan, China.
Yilong WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yong WangDepartment of Radiology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Zheng WangSchool of Psychological and Cognitive Sciences, Peking University, Beijing, China.ORCID http://orcid.org/0000-0001-7138-8581
Jinyuan WengPhilips (China) Investment, Shanghai, China.
Feiyun WuDepartment of Radiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Ying WuSchool of Medical Imaging, Shanxi Medical University, Taiyuan, China.ORCID http://orcid.org/0009-0008-3538-6720
Yuankui WuDepartment of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Haiyan WuCentre for Cognitive and Brain Sciences and Department of Psychology, University of Macau, Macau, China.ORCID http://orcid.org/0000-0001-8869-6636
Xiaona XiaDepartment of Radiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, China.
Cheng XuDepartment of Imaging, Shanxi Provincial People's Hospital, Taiyuan, China.
Jiaheng XuDepartment of Radiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Jun XuDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Rui XuDepartment of Radiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Siyao XuDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Panjie YanState Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, Beijing, China.
Ruimeng YangDepartment of Radiology, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China.
SongTao YinDepartment of Imaging Medicine, Inner Mongolia Autonomous Region People's Hospital, Hohhot, China.
Xi YinMedical Imaging Center, The First Affiliated Hospital of Shihezi University, Shihezi, China.
Yulong YinSchool of Psychology, Northwest Normal University, Lanzhou, China.
Rongjun YuLife Science Imaging Center, Hong Kong Baptist University, Hong Kong, China.ORCID http://orcid.org/0000-0003-0123-1524
Zhen YuanCentre for Cognitive and Brain Sciences and Department of Psychology, University of Macau, Macau, China.ORCID http://orcid.org/0000-0003-3061-6263
Feifei ZhangDepartment of Radiology, First Hospital of Shanxi Medical University, Taiyuan, China.
Hailian ZhangDepartment of Radiology, The Fifth People's Hospital of Qinghai Province, Xining, China.
Jianguo ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0002-0009-0574
Ningnannan ZhangDepartment of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, Tianjin, China.
Renlong ZhangInstitute of Research and Clinical Innovations, Neusoft Medical Systems, Beijing, China.ORCID http://orcid.org/0009-0008-1165-1331
Tong ZhangDepartment of Radiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Yaqin ZhangDepartment of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Zhanjun ZhangState Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, Beijing, China.ORCID http://orcid.org/0000-0001-7266-4218
Zhiqiang ZhangDepartment of Diagnostic Radiology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.ORCID http://orcid.org/0000-0002-3993-7330
Zhihua ZhangDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jian ZhaoDepartment of Radiology, Hebei Medical University Third Hospital, Shijiazhuang, China.
Lianping ZhaoDepartment of Radiology, Gansu Provincial Hospital, Lanzhou, China.
Xiaohu ZhaoDepartment of Radiology, The Fifth People's Hospital of Shanghai Fudan University, Shanghai, China.
Xinxiang ZhaoDepartment of Radiology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Xin ZhaoSchool of Psychology, Northwest Normal University, Lanzhou, China.
Xia ZheDepartment of MRI, Shaanxi Provincial People's Hospital, Xi'an, China.
Fuqing ZhouDepartment of Radiology, The First Affiliated Hospital, Nanchang University, Nanchang, China.
Jiajia ZhuDepartment of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID http://orcid.org/0000-0001-7343-6241
Li ZhuDepartment of Radiology, General Hospital of Ningxia Medical University, Yinchuan, China.
Kuncheng LiDepartment of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xujun DuanThe Clinical Hospital of Chengdu Brain Science Institute, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.ORCID http://orcid.org/0000-0001-8543-2117
Yunyun DuanDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xi-Nian ZuoState Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, Beijing, China. xinian.zuo@bnu.edu.cn.ORCID http://orcid.org/0000-0001-9110-585X
Yaou LiuDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. liuyaou@bjtth.org.ORCID http://orcid.org/0000-0003-4352-5774
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quantifying individual deviations in brain morphology from normative references is useful for understanding neurodiversity and facilitating personalized management of brain health. Here we report Chinese brain normative references using morphological imaging scans of 24,061 healthy volunteers from 105 sites, revealing later peak ages of lifespan neurodevelopmental milestones (1.2-8.9 years) than European/North American populations. We model individual brain deviation scores in 3,932 individuals with different neurological disorders from population references to evaluate three key aspects of brain health assessment using machine learning approaches: estimating disease propensity, predicting cognitive and physical outcomes and assessing treatment effects with distinct disability progression. The norm-deviation scores outperformed raw structural measures in these evaluations. Chinese-specific normative brain references may foster personalized diagnosis and prognosis in neurological diseases, enabling clinically applicable assessments of brain health.
Indexed as
BrainNervous System DiseasesAdolescentAdultAgedChildChild, PreschoolFemaleHumansInfantMachine LearningMagnetic Resonance ImagingMaleMiddle AgedYoung Adult
Identifiers
PMID
41461930What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.