Evidence map›Paper›PMID 41461764›Full record

ArticleScientific reports2025

Molecular characterization of bovine leukemia virus detected in dairy cattle herds from the Emirate of Abu Dhabi, United Arab Emirates.

Nabeeha A Hassan, Hassan Z Ishag, Asha Anthony, Aboma Zewude, Anthony W Wamono, Ibrahim M Abdalla-Alfaki, Amira Mohammed, Persabiel Tesfay, Lamek Shikoray, Hend A M Almohsen and 8 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Nabeeha A HassanDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE.
Hassan Z IshagBiosecurity Affairs Division, Abu Dhabi Agriculture & Food Safety Authority, Abu Dhabi, UAE.
Asha AnthonyDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE.
Aboma ZewudeDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE.
Anthony W WamonoRIVUS Consulting LLC, 6212 Seabrook Road, Lanham, MD, 20706, USA.
Ibrahim M Abdalla-AlfakiDepartment of Statistics and Business Analytics, College of Business and Economics, United Arab Emirates University, Al Ain, UAE.
Amira MohammedDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE.
Persabiel TesfayDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE.
Lamek ShikorayDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE.
Hend A M AlmohsenDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE.
Yousef M AlramahiDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE.
Meera S AlKalbaniExtension Services & Animal Health Division, Abu Dhabi Agriculture & Food Safety Authority, Abu Dhabi, UAE.
Oum K BensalahBiosecurity Affairs Division, Abu Dhabi Agriculture & Food Safety Authority, Abu Dhabi, UAE.
Shamma A AlnaqbiExtension Services & Animal Health Division, Abu Dhabi Agriculture & Food Safety Authority, Abu Dhabi, UAE.
Mohammed S AlBreikiBiosecurity Affairs Division, Abu Dhabi Agriculture & Food Safety Authority, Abu Dhabi, UAE.
Asma Mohammed A ShahBiosecurity Affairs Division, Abu Dhabi Agriculture & Food Safety Authority, Abu Dhabi, UAE.
Gobena AmeniDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE. gobena.ameni@uaeu.ac.ae.
Robert BarigyeDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE. rbarigye@uaeu.ac.ae.

Funding

United Arab Emirates University G00003833
6 · The paper itself

Abstract

Enzootic bovine leukosis (EBL) is an economically important disease of cattle caused by the bovine leukemia virus (BLV). Although BLV-seropositive dairy cattle were previously reported in the Emirate of Dhabi, UAE (EAD), molecular characterization of circulating BLV strains has not been undertaken. Therefore, the objectives of this study were to reassess the seroprevalence along with evaluating the genetic diversity of BLV strains circulating in dairy cattle in the EAD. Sera from 782 dairy cattle distributed across 11 farms were ELISA-screened and RT-qPCR testing of seropositive samples was followed by Sanger sequencing of the partial BLV env-gp51 gene (~ 423 bp) and phylogenetic analysis. The overall BLV herd seroprevalence was 27.3% (CI: 6.03%-61.00%), mean animal seroprevalence 33.5% (CI:30.20%-36.93%), and individual farm seroprevalence 28.00% (CI:19.00%-36.00%), 70.00% (CI:56.00%-84.00%), and 64.00% (59.00%-70.00%) for Farms 7, 11, and 14 respectively. Viral RNA was detected in 107 of 205 (52.2%) seropositive cattle, and phylogenetic analysis revealed a high genetic relatedness (~ 99.3-100.0%) among the BLV strains from the EAD. Additionally, study BLV isolates cluster under BLV-genotype 4 along with strains from Belgium, Russia and Vietnam. BLV infection is confirmed in EAD cattle, with circulating genotype 4 strains closely related to those from Europe and Asia, suggesting potential transboundary connections and underscoring the need for coordinated regional control measures. Future studies should focus on characterizing BLV infection risk factors in dairy cattle farms in the EAD. In the meantime, UAE livestock health authorities should urgently consider developing a national EBL control policy.

Indexed as

Enzootic Bovine LeukosisLeukemia Virus, BovineAnimalsAntibodies, ViralCattleDairyingFemaleGenetic VariationPhylogenySeroepidemiologic StudiesUnited Arab EmiratesAntibodies, ViralAbu Dhabi EmirateBovine leukaemia virusCattleEnzootic bovine leukosisUAE

Identifiers

PMID41461764
PMCPMC12748790

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.