Evidence map›Paper›PMID 41461740›Full record

ArticleScientific reports2025

Efficacy of laparoscopic bailout surgery for moderate and severe acute cholecystitis.

Nao Kitasaki, Tomoyuki Abe, Tsuyoshi Kobayashi, Naruhiko Honmyo, Shintaro Kuroda, Michinori Hamaoka, Daisuke Takei, Takashi Onoe, Toshihiko Kohashi, Koichi Oishi and 1 more

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Nao KitasakiDepartment of Gastroenterological Surgery, National Hospital Organization (NHO) Higashihiroshima Medical Center, Hiroshima, Japan.
Tomoyuki AbeDepartment of Gastroenterological Surgery, National Hospital Organization (NHO) Higashihiroshima Medical Center, Hiroshima, Japan. t.abe.hiroshima@gmail.com.
Tsuyoshi KobayashiDepartment of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.
Naruhiko HonmyoDepartment of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.
Shintaro KurodaDepartment of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.
Michinori HamaokaDepartment of Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan.
Daisuke TakeiDepartment of Surgery, Onomichi General Hospital, Onomichi, Japan.
Takashi OnoeDepartment of Surgery, Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Toshihiko KohashiDepartment of Surgery, Hiroshima City Asa Citizens Hospital, Hiroshima, Japan.
Koichi OishiDepartment of Surgery, Chugoku Rosai Hospital, Kure, Japan.
Hideki OhdanDepartment of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

"Bailout surgery" (BOS) refers to specific surgical maneuvers implemented to safely manage difficult acute cholecystitis (AC) cases and prevent complications, including massive bleeding or bile duct injury (BDI). This study validated laparoscopic BOS (lap-BOS) in moderate to severe AC cases requiring BOS. Overall, 547 patients with moderate and severe AC diagnosed per Tokyo Guideline 2018 (TG18) were retrospectively analyzed from 2020 to 2023. Of these, 129 underwent BOS, and 418 conventional laparoscopic cholecystectomy (Lap-C). Perioperative outcomes between Lap-C and BOS were compared. Patients who underwent BOS were divided into lap-BOS and conversion to open surgery (CO) groups. Patients in the BOS group were older and had higher Charlson comorbidity index scores than those in the Lap-C group. Intraoperative blood loss and operative times the rate of postoperative bile leakage were worse in the BOS group than Lap-C group. Among BOS group, the Lap-BOS group had shorter operative times, less blood loss and lower rates of complications than CO groups. BDI, postoperative bile leakage and the modified Nassar difficulty grading scales were comparable between the Lap-BOS and CO groups. Although, no differences were observed in BDI or postoperative bile leakage among Lap-C and Lap-BOS. Lap-BOS would be beneficial in avoiding common bile duct injury as for TG18 moderate and severe AC. In difficult AC cases, Lap-BOS is an alternative strategy to prevent bile duct injury of common bile duct requiring surgical intervention postoperative bile leakage and reduce intraoperative time and intraoperative bleeding rather than CO.

Indexed as

Cholecystectomy, LaparoscopicCholecystitis, AcuteAdultAgedBlood Loss, SurgicalFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsRetrospective StudiesSeverity of Illness IndexTreatment OutcomeBailout surgeryLaparoscopic cholecystectomyTokyo guidelines 2018

Identifiers

PMID41461740
PMCPMC12750002

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.