Evidence map›Paper›PMID 41461670›Full record

ArticleScientific reports2025

Nonlinear effects of ambient temperature and treatment days on nocturnal enuresis using generalized additive models.

Teruo Miyano, Takahiro Arai, Yuta Onuki, Tomoko O Morita, Hirokazu Ikeda

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Teruo Miyano *Japan Data Science Research Institute, 3F Kato Building, 1-9-18 Hiroo, Shibuya-ku, Tokyo, 150-0012, Japan. teruo.miyano@keio.jp.
Takahiro Arai *Japan Data Science Research Institute, 3F Kato Building, 1-9-18 Hiroo, Shibuya-ku, Tokyo, 150-0012, Japan.
Yuta OnukiChildren's Center, Showa Medical University Northern Yokohama Hospital, Yokohama, Kanagawa, 224-8503, Japan.
Tomoko O MoritaJapan Data Science Research Institute, 3F Kato Building, 1-9-18 Hiroo, Shibuya-ku, Tokyo, 150-0012, Japan.
Hirokazu IkedaChildren's Center, Showa Medical University Northern Yokohama Hospital, Yokohama, Kanagawa, 224-8503, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To examine the effects of the average daily ambient temperature and treatment days on the outcomes of patients with nocturnal enuresis (NE), a common urinary symptom in children. The panel data of 19 children with NE (12 boys and 7 girls; median age: 9 years; age range: 6-15) were prospectively collected (up to 1,469 days; total number of records: 3194). NE status (presence of incontinence), treatment type, and weather-related variables (ambient temperature, precipitation, sunshine hours, and barometric pressure) were recorded. Factor analyses were subsequently performed using a generalized additive model (GAM). Among the patient features, treatment type, and weather-related variables, the average daily ambient temperature and treatment days were identified as risk factors for NE. Specifically, NE risk increased with an average daily ambient temperature of < 16.7 °C and decreased with a daily average ambient temperature of > 20.1 °C. An inverse correlation between NE risk and treatment days was observed in all cases. Notably, long-term treatment of approximately ≥ 1465 days significantly reduced the NE risk, despite repeated exacerbations. The average daily ambient temperature and treatment days affect the risk of NE.

Indexed as

Nocturnal EnuresisTemperatureAdolescentChildFemaleHumansMaleProspective StudiesRisk FactorsBed-wettingChildrenTreatment daysWeather conditions

Identifiers

PMID41461670
PMCPMC12748616

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.