Evidence map›Paper›PMID 41461666›Full record

ArticleScientific reports2025

Development and application of whole-herd-sampling, qPCR-based-testing, and precision-removal methods to eliminate ASFV in four large swine herds in China.

Xiaowen Li, Peng Li, Bingzhou Zhang, Weisheng Wu, Junxian Li, Wenchao Gao, Jincheng Yu, Mingyu Fan, Yunzhou Wang, Qiannan Yu and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xiaowen LiCollege of Veterinary Medicine, Northwest A&F University, Xianyang, Yangling, China. lxw8272@163.com.
Peng LiXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Bingzhou ZhangXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Weisheng WuXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Junxian LiXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Wenchao GaoXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Jincheng YuXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Mingyu FanCollege of Veterinary Medicine, Northwest A&F University, Xianyang, Yangling, China.
Yunzhou WangXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Qiannan YuXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Jintao LiXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Xiaoyang ZhangXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China.
Qingyuan LiuCollege of Veterinary Medicine, Northwest A&F University, Xianyang, Yangling, China.
Lili WuCollege of Veterinary Medicine, Northwest A&F University, Xianyang, Yangling, China.
Xinglong WangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, Yangling, China. wxlong@nwsuaf.edu.cn.
Zhichun YanXiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd., Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Dezhou, China. Jasonynh@126.com.

Funding

CARS CARS-35the Taishan Industry Leadership Talent Project of Shandong Province in China tscx202306093
6 · The paper itself

Abstract

Since the first ASFV case was reported in China in 2018, troditional control stategies involving whole-herd culling upon detection of ASFV positivity have proved unwieldy because of its high production intensity and complex trade network. To provide an alternative to conventional stamping-out methods, we developed a novel approach termed "Whole-herd-Sampling, qPCR-based-Testing, and Precision-Removal" method. This approach involves whole herd sampling and qPCR testing to determine the status of ASFV in herds, followed by the precision removal of identified infected sows. By applying these techniques, we successfully controlled ASF and eliminated the virus from 4 large swine herds between 2019 and 2020. The time to negative herd (TTNH) was 19, 28, 14, and 1 day from farm 1 to 4, respectively. Retention rates of pigs from farm 1 to farm 4 were 69.7%, 65%, 99.4%, and 99.72%, respectively. We propose that this innovative method would be a good alternative to the conventional stamping-out strategies and greatly facilitate the control and eradication of ASFV both in China and worldwide.

Indexed as

African Swine FeverAfrican Swine Fever VirusReal-Time Polymerase Chain ReactionAnimalsChinaSwineAfrican swine fever virusQuantitative PCRTest removal

Identifiers

PMID41461666
PMCPMC12749460

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.