Evidence map›Paper›PMID 41461582›Full record

ReviewBritish journal of pharmacology2025

The Concise Guide to PHARMACOLOGY 2025/26: Nuclear hormone receptors.

Stephen P H Alexander, John A Cidlowski, Alasdair J Gibb, Eamonn Kelly, Alistair A Mathie, Chloe J Peach, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding and 11 more

Abstract readReview
In one paragraph

Review in British journal of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Stephen P H AlexanderDivision of Physiology, Pharmacology & Neuroscience, School of Life Sciences, University of Nottingham Medical School, Nottingham, NG7 2UH, UK.ORCID https://orcid.org/0000-0003-4417-497X
John A CidlowskiNational Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.ORCID https://orcid.org/0000-0003-1420-0516
Alasdair J GibbResearch Department of Neuroscience, Physiology and Pharmacology, Division of Biosciences, University College London, Gower Street, London, WC1E 6BT, UK.ORCID https://orcid.org/0000-0002-2145-1615
Eamonn KellySchool of Psychology and Neuroscience, University of Bristol, Bristol, BS8 1TD, UK.ORCID https://orcid.org/0000-0002-9183-3993
Alistair A MathieSchool of Life Sciences, University of Westminster, London, W1W 6UW, UK.ORCID https://orcid.org/0000-0001-6094-2890
Chloe J PeachDivision of Physiology, Pharmacology & Neuroscience, School of Life Sciences, Centre of Membrane Proteins and Receptors (COMPARE), University of Nottingham Medical School, Nottingham, NG7 2UH, UK.ORCID https://orcid.org/0000-0001-6315-1170
Emma L VealeMedway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, Kent, ME4 4TB, UK.ORCID https://orcid.org/0000-0002-6778-9929
Jane F ArmstrongInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID https://orcid.org/0000-0002-0524-0260
Elena FaccendaInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID https://orcid.org/0000-0001-9855-7103
Simon D HardingInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID https://orcid.org/0000-0002-9262-8318
Christopher SouthanInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID https://orcid.org/0000-0001-9580-0446
Jamie A DaviesInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID https://orcid.org/0000-0001-6660-4032
Laurel CoonsDuke University Medical Center, Durham, USA.
Peter J FullerHudson Institute of Medical Research, Clayton, Australia.
Kenneth S KorachNational Institutes of Health, Research Triangle Park, USA.
Donald P McDonellDuke University School of Medicine, Durham, USA.
Robert OakleyNational Institutes of Health, Research Triangle Park, USA.
Sarah RadiUniversity of California, Riverside, Riverside, USA.ORCID https://orcid.org/0009-0006-5877-7033
Rachid SafiDuke University School of Medicine, Durham, USA.
Frances SladekUniversity of California, Riverside, Riverside, USA.ORCID https://orcid.org/0000-0001-8346-8474
Morag J YoungMonash University, Melbourne, Australia.

Funding

GLUCOCORTICOID HORMONE ACTIONZ01ES090057 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI CIDLOWSKI, JOHN A. · 1996 to 2008
$4.1M
Intramural NIH HHS Z01 ES090057
6 · The paper itself

Abstract

The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear, accessible, and well-structured, rather than the scope of the content, which spans approximately 500 pages. The Concise Guide summarises the key pharmacological properties of around 1900 human drug targets, and nearly 7000 interactions, involving around 4400 ligands. While the content is a substantially condensed version of the more detailed information and links available at the www.guidetopharmacology.org website, the printed guide serves as a permanent, citable, point-in-time record, that remains stable despite ongoing updates to the online database. The full contents of this publication can be found at https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70232. The Concise Guides provide expert-curated recommendations of 'Gold Standard' selective pharmacological tools, available either commercially or as donations, which enable the identification of individual drug targets or families of drug targets. While the Concise Guide offers a more streamlined overview, more comprehensive information, including detailed pharmacological profiles and links to multiple online databases, is available through the Guide to Pharmacology website. The 2025/26 edition of the Concise Guide is based on material current as of mid-2025, and supersedes all previous editions, including the 2023/24 Guide, and earlier Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), and as such provides official IUPHAR classification and nomenclature for human drug targets, where applicable. Nuclear hormone receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, catalytic receptors, enzymes and transporters. Each section includes nomenclature guidance, concise summaries information of the best available pharmacological tools, key references, and suggestions for further reading.

Indexed as

Receptors, Cytoplasmic and NuclearAnimalsHumansLigandsPharmacologyLigandsReceptors, Cytoplasmic and Nuclear

Identifiers

PMID41461582
PMCPMC13474312

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.