Evidence map›Paper›PMID 41461562›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2025

[Research progress on bioartificial liver].

Q Jiang, Y S Su, X Y Cao, H N Zhang, L J Li

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Q JiangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China Research Units of Infectious Disease and Microecology, Chinese Academy of Medical Sciences & Peking Union Medical College, Hangzhou 310003, China Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 102600, China.
Y S SuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
X Y CaoInstitute of Obstetrics and Gynecology, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai 200080, China.
H N ZhangDepartment of Ultrasound, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
L J LiState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China Research Units of Infectious Disease and Microecology, Chinese Academy of Medical Sciences & Peking Union Medical College, Hangzhou 310003, China.

Funding

Central Guidance Fund for Local Science and Technology Development 2024ZY01054Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences 2019-I2M-5-045Fundamental Research Funds for the Central Universities 2022ZFJH003
6 · The paper itself

Abstract

Liver failure is severe liver damage caused by multiple factors, with a very high mortality rate. Artificial liver support systems have become a core strategy for alternative or bridging therapy in the context of the rapid progression of liver failure and high mortality rates with comprehensive internal medicine therapy. Non-bioartificial livers mainly serve as partial substitutes for liver function improvement through procedures such as perfusion, dialysis, and filtration methods. Bioartificial livers provide liver support therapy for patients by integrating detoxification, synthesis, and metabolic functions to simulate hepatic biosynthesis, filling the gap that non-bioartificial livers cannot perform and addressing the difficulties of non-bioartificial livers' heavy reliance on blood products. This paper focuses on reviewing the basic and clinical research progress of bioartificial livers, providing a multidimensional perspective to accelerate their clinical translation.

Indexed as

Liver, ArtificialLiver FailureHumansLiver

Identifiers

PMID41461562
PMCPMC12817054

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.