ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2025
[Clinical research advances for small-molecule nucleic acid drugs in the treatment of chronic hepatitis B].
Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Currently, the commonly used antiviral drugs for hepatitis B virus (HBV) primarily include nucleos(t)ide analogues and interferons, which effectively suppress viral replication but typically have difficulty achieving clinical cure of chronic hepatitis B (CHB). Recent clinical trials have demonstrated that small-molecule nucleic acid drugs have favorable safety profiles for CHB treatment. Thus, these drugs have the potential to become a novel breakthrough point in CHB and demonstrate promising prospects in terms of clinical cure by inducing the degradation of viral RNA and activating the body's immune response to clear hepatitis B surface antigen. This review summarized the current clinical research advances for small-molecule nucleic acid drugs in the treatment of CHB.
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