Evidence map›Paper›PMID 41461551›Full record

ArticleZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2025

[Clinical research and medical ethics in the era of artificial intelligence].

X Song, N Gao, K Q Huang, X Y Chen, S J Deng, C Xie, L Peng

Abstract readEnglish Abstract
In one paragraph

Article in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

X SongDepartment of Infectious Diseases, Guangdong Provincial Key Laboratory of Liver Disease Research, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
N GaoDepartment of Infectious Diseases, Guangdong Provincial Key Laboratory of Liver Disease Research, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
K Q HuangEthics Committee Office, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
X Y ChenDepartment of Infectious Diseases, Guangdong Provincial Key Laboratory of Liver Disease Research, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
S J DengDepartment of Infectious Diseases, Guangdong Provincial Key Laboratory of Liver Disease Research, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
C XieDepartment of Infectious Diseases, Guangdong Provincial Key Laboratory of Liver Disease Research, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
L PengDepartment of Infectious Diseases, Guangdong Provincial Key Laboratory of Liver Disease Research, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.

Funding

Five-Year Plan of Third Affiliated Hospital of Sun Yat-Sen University 2023W106Guangdong Basic and Applied Basic Research Foundation 2023A1515110584Guangzhou Science and Technology Program Key Projects 2023B03J1287, 2023B01J1007Major Special Projects for Four Major Chronic Diseases 2024ZD0526202Natural Science Foundation of China 82070611, 82500749
6 · The paper itself

Abstract

Artificial intelligence (AI), a core technology of the Fourth Industrial Revolution, profoundly reshapes the landscape of modern medicine. AI can extract information from extensive datasets, optimizing trial design, and enhancing research efficiency. It is widely applied in field such as medical imaging, clinical decision support, precision medicine, and drug development. Notably, AI brings revolutionary opportunities to clinical research and practice; however, it also raises a series of serious ethical and regulatory challenges regarding data privacy, algorithmic bias, attribution of responsibility, and informed consent. This article systematically discusses the current applications of AI at various stages of clinical research, deeply analyzes the core ethical dilemmas arising from these applications, and outlines corresponding ethical governance frameworks and response strategies. In addition, we advocated establishment of a collaborative governance system that is people-oriented and technology-driven, emphasizing strict adherence to ethical principles throughout the entire process of technological development to ensure the scientific, fair, and safe nature of clinical research, ultimately resulting in the coordinated progress of artificial intelligence technology and medical ethics.

Indexed as

Artificial IntelligenceBiomedical ResearchEthics, MedicalHumansInformed ConsentPrecision Medicine

Identifiers

PMID41461551
PMCPMC12817055

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.