Evidence map›Paper›PMID 41461539›Full record

ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2026

[U-shaped association between hematocrit and resting pulse oxygen saturation in Tibetan plateau population].

Yimei Guo, Ronghui Li, Ciren Laba, Qi Yan

Abstract readEnglish Abstract
In one paragraph

Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yimei GuoDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, Lhasa 850002, China. 593594572@qq.com.
Ronghui LiDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, Lhasa 850002, China.
Ciren LabaDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, Lhasa 850002, China.
Qi YanDepartment of Anesthesiology, Tibet Autonomous Region People's Hospital, Lhasa 850002, China. yanqi04@pku.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the relationship between hematocrit (HCT) and low resting oxygen saturation in Tibetan plateau population.

methodsThis retrospec-tive cohort study included 3075 Tibetan adult inpatients who underwent elective non-cardiac, non-thoracic surgery at Tibet Autonomous Region People's Hospital between January 2023 and October 2024. Multivariate logistic regression was used to assess the association between HCT and low resting oxygen saturation (SpO

resultsMultivariate logistic regression analysis showed that elevated HCT was an independent risk factor for low oxygen saturation in the patients. For every 5-percentage-point increase in HCT, the risk of low oxygen saturation increased by 12% (

conclusionsThere is a U-shaped association between HCT and low resting oxygen saturation in the Tibetan plateau population. An HCT level exceeding the population-specific threshold suggests that the adaptive erythropoietic response to high-altitude hypoxia may transition from being compensatory to potentially detrimental.

Indexed as

OxygenOxygen SaturationAdultAgedAltitudeFemaleHematocritHumansLogistic ModelsMaleMiddle AgedRetrospective StudiesRisk FactorsTibetOxygenHealth managementHematocritHigh-altitude populationPulse oxygen saturationRetrospective studyU-Shaped association

Identifiers

PMID41461539
PMCPMC12972866

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.