Evidence map›Paper›PMID 41461150›Full record

ArticleTropical medicine & international health : TM & IH2026

A National Survey of Adherence to Glucose-Lowering Medication Among Adults With Diabetes in Indonesia.

Nora Wulandari, Rachmadianti Sukma Hanifa, Spyros Balafas, Muhamad Syaripuddin, Mahalul Azam, Sudibyo Supardi, Jurjen van der Schans, Talitha Feenstra, Katja Taxis

Abstract read
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nora WulandariUnit of Pharmaco-Therapy, -Epidemiology, and -Economics (PTEE), Faculty of Science and Engineering, University of Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-9004-7061
Rachmadianti Sukma HanifaUnit of Global Health, Department of Health Sciences, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0009-0006-4305-2478
Spyros BalafasUnit of Pharmaco-Therapy, -Epidemiology, and -Economics (PTEE), Faculty of Science and Engineering, University of Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0003-1590-2093
Muhamad SyaripuddinDirektorat Mutu Dan Fasilitas, Dirjend Kesehatan Masyarakat, Ministry of Health of Indonesia, Jakarta, Indonesia.
Mahalul AzamDepartemt of Public Health, Faculty of Medicine, Universitas Negeri Semarang, Semarang, Indonesia.ORCID https://orcid.org/0000-0002-2441-5433
Sudibyo SupardiNational Research and Innovation Agency (BRIN), Health Research Organization, Jakarta, Indonesia.
Jurjen van der SchansUnit of Global Health, Department of Health Sciences, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-6170-1191
Talitha FeenstraUnit of Pharmaco-Therapy, -Epidemiology, and -Economics (PTEE), Faculty of Science and Engineering, University of Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0002-5788-0454
Katja TaxisUnit of Pharmaco-Therapy, -Epidemiology, and -Economics (PTEE), Faculty of Science and Engineering, University of Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-8539-2004

Funding

The Indonesian Education Scholarship (BPI) from the Center for Higher Education Funding and Assessment (PPAPT) and Indonesia Endowment Funds for Education (LPDP) 3004/BPPT/BPI.LG/IV/2024
6 · The paper itself

Abstract

backgroundNon-adherence to medication is a major challenge for patients with diabetes. Despite the growing burden of diabetes in Indonesia, nation-wide research on medication adherence remains limited.

objectiveTo identify factors associated with adherence to glucose-lowering medication among adults with diabetes in Indonesia.

methodsThis cross-sectional study used data from the 2023 Indonesian National Health Survey (SKI), a nationwide survey using a stratified, multi-stage sampling method with probability-proportional-to-size household selection collecting data by personal interview at home. Respondents with diabetes using glucose-lowering medication were included. Multiple logistic regression for complex sample analysis was used to model the adherence to glucose-lowering medication, ensuring population-level representativeness and exploring the factors associated with adherence.

resultsOf 13,960 respondents, 12.3% were non-adherent. Regular follow-ups at health facilities showed the strongest association with adherence (OR = 11.56, 95% CI: 8.74-15.27, p < 0.001). Other significant factors included receiving medication from medical personnel (OR = 4.13, 95% CI: 3.25-5.26, p < 0.001), insulin use (OR = 2.74, 95% CI: 1.76-4.27, p < 0.001), self-purchasing medication (OR = 1.5, 95% CI: 1.17-1.91, p = 0.001), receiving diabetes management education (OR = 1.46, 95% CI: 1.20-1.79, p < 0.001), maintaining a healthy diet (OR = 1.57, 95% CI: 1.26-1.95, p < 0.001), and regular exercise (OR = 1.34, 95% CI: 1.10-1.65, p < 0.001). In contrast, herbal medicine use was negatively associated with adherence (OR = 0.54, 95% CI: 0.44-0.65, p = 0.005).

conclusionsMedication adherence is associated with a combination of treatment and healthcare system/healthcare provider-related factors. Improved patients' engagement and better access to glucose-lowering medications could increase medication adherence.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2Hypoglycemic AgentsMedication AdherenceAdolescentAdultAgedCross-Sectional StudiesFemaleHealth SurveysHumansIndonesiaMaleMiddle AgedYoung AdultHypoglycemic Agentscross‐sectional/surveydiabetesherbal medicineIndonesiamedication adherence

Identifiers

PMID41461150
PMCPMC12963041

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.