Evidence map›Paper›PMID 41461030›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Evaluating inbreeding and assessing the risk of outbreeding depression in genetic rescue using whole-genome sequence data.

Aja Noersgaard Buur Tengstedt, Toke Thomas Høye, Torsten Nygaard Kristensen, Michael M Hansen

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genetic Rescue: Latest Advances and Applications.Evolutionary applications · 2026
    Article
  8. Genomics and genetic rescue.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Aja Noersgaard Buur TengstedtDepartment of Biology, Aarhus University, Aarhus C DK-8000, Denmark.ORCID 0000-0002-2525-159X
Toke Thomas HøyeDepartment of Ecoscience and Arctic Research Center, Aarhus University, Aarhus C DK-8000, Denmark.ORCID 0000-0001-5387-3284
Torsten Nygaard KristensenDepartment of Chemistry and Bioscience, Aalborg University, Aalborg Øst DK-9220, Denmark.ORCID 0000-0001-6204-8753
Michael M HansenDepartment of Biology, Aarhus University, Aarhus C DK-8000, Denmark.ORCID 0000-0001-5372-4828

Funding

15. Juni Fonden (June 15 Funds) 2014-A-1315. Juni Fonden (June 15 Funds) 2017-N-6Aalborg Zoos Naturbevaringsfond (AZCF) 0000000000Danmarks Frie Forskningsfond (DFF) 1026-00056BDanmarks Grundforskningsfond (DNRF) DNRF173
6 · The paper itself

Abstract

Restoring genetic diversity through assisted migration is increasingly recognized as a crucial strategy to counteract inbreeding depression and boost genetic variation in small and fragmented populations yet concerns about outbreeding depression often hinder its application. We propose a genomics-informed update to an existing framework enabling a more precise assessment of outbreeding depression risk and genetic rescue feasibility. We apply this approach to a butterfly species-the marsh fritillary (

Indexed as

ButterfliesInbreedingInbreeding DepressionAnimalsConservation of Natural ResourcesDenmarkEndangered SpeciesGene FlowGenetic VariationGenomicsPopulation DynamicsWhole Genome Sequencingdemographic historygenetic rescueinbreedinglocal adaptationoutbreeding depression

Identifiers

PMID41461030
PMCPMC12773729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.