Evidence map›Paper›PMID 41460912›Full record

ArticleOrthopaedic surgery2026

Extraarticular Knee Joint Resection: Indications, Results, and Complications in a Series of 30 Patients.

Carmine Zoccali, Giuseppe Francesco Papalia, Giovanni Cepparulo, Jacopo Baldi, Francesca Sperati, Andrea Amendola, Nicola Salducca, Stefano Gumina

Abstract read
In one paragraph

Article in Orthopaedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carmine ZoccaliDepartment of Anatomical, Histological, Forensic Medicine and Orthopedic Science, University of Rome, Rome, Italy.
Giuseppe Francesco PapaliaOncological Orthopedics Department, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.ORCID https://orcid.org/0000-0002-4140-738X
Giovanni CepparuloDepartment of Anatomical, Histological, Forensic Medicine and Orthopedic Science, University of Rome, Rome, Italy.
Jacopo BaldiOncological Orthopedics Department, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Francesca SperatiOncological Orthopedics Department, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Andrea AmendolaDepartment of Radiological, Oncological and Pathological Sciences, Sapienza, University of Rome, Rome, Italy.
Nicola SalduccaOncological Orthopedics Department, IRCCS - Regina Elena National Cancer Institute, Rome, Italy.
Stefano GuminaDepartment of Anatomical, Histological, Forensic Medicine and Orthopedic Science, University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWide surgical resection is the standard for primary malignant soft tissue and bone tumors, especially when the knee's intra-articular space is involved. Extraarticular Knee Joint Resection (EKJR) aims to remove the knee joint while preserving function. Considering the lack of literature present on these aspects, the purpose of this study is to analyze the data of a series of 30 patients affected by benign aggressive or malignant bone and soft tissue tumors who underwent EKJR with two different resection techniques.

methodsThe study involved all patients treated with EKJR for tumors between October 2006 and March 2023. Two EKJR techniques were analyzed: Type-A (complete extensor mechanism excision) and Type-B (patellar coronal osteotomy sparing the extensor mechanism). Clinical outcomes, tumor characteristics, and complications were compared between the two techniques. For statistical analyses, the Mann-Whitney test or Kruskal-Wallis test was employed to explore differences between continuous variables. Relationships between categorical variables were assessed using Pearson's Chi-square test or Fisher's exact test. Correlations were evaluated using Spearman's correlation coefficient. Survival analyses were conducted using the Kaplan-Meier method.

resultsThe cohort included 13 males and 17 females (16 Type-A, 14 Type-B resections). Histologically confirmed intra-articular involvement was found in 26.7% of cases. Late complications included infections and amputations, more frequently in Type-A resections. The 5-year Local Recurrence-Free Survival was 91.5%, Metastasis-Free Survival was 39.5%, and Overall Survival was 47.9%. Type-A resections lead to higher complication rates, including amputation, due to extensive vascular and tissue disruption. Type-B resections, preserving the extensor mechanism, result in better functional outcomes and faster recovery despite some residual weakness.

conclusionEKJR is oncologically effective but carries significant functional and complication considerations. Type-B resection balances oncological safety and functional preservation, especially for benign aggressive tumors.

Indexed as

Bone NeoplasmsKnee JointOsteotomySoft Tissue NeoplasmsAdolescentAdultAgedChildFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeYoung Adultbone tumorsextensor mechanism reconstructionextra‐articular joint resectionknee joint resectionsoft tissue tumorswide surgery

Identifiers

PMID41460912
PMCPMC12862440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.