Trial reportActa odontologica Scandinavica2025
Fluoridated milk is effective in prevention of enamel caries in adolescents: a randomised trial.
Trial report in Acta odontologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06684405 (Fluoridated Milk is Effective in Prevention of Enamel Caries in Adolescents), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Fluoridated Milk is Effective in Prevention of Enamel Caries in Adolescents
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate whether low daily doses of fluoridated milk, as an adjunct to oral hygiene routines with fluoridated toothpaste, can prevent caries development in enamel and dentine in adolescents. MATERIAL AND
methodsAdolescents (mean age 13 years) at three dental clinics in Sweden were enrolled to a randomised clinical trial (RCT) including baseline and 2-year follow-up examinations. The intervention group consumed milk supplemented with fluoride (0.75-1.0 mg) daily, while the control group consumed milk with water. Caries lesion development was assessed visually in line with the international caries detection and assessment system (ICDAS), except for proximal surfaces of premolars and molars which were assessed using a radiological classification system. Outcome measures were decayed, missing and filled surfaces (DMFS) increment, caries lesion arrest and progression.
resultsEighty seven participants in the intervention group and 72 in the control group completed the study. The intervention reduced the incidence of DMFS increment for enamel lesions, but not for dentine lesions. The degree of caries lesion arrest in outer enamel was higher in the intervention group compared to the control group, whereas caries lesion progression was lower in the intervention group.
conclusionFluoride exerts an effect on caries lesions in the outer enamel, and fluoridated milk thus can be beneficial to adolescents with such lesions.
trial registrationClinicaltrials.gov registration number NCT06684405.
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