Evidence map›Paper›PMID 41460584›Full record

ArticleNeurosurgical review2025

Efficacy and safety of external ventricular drainage in the treatment of space-occupying cerebellar infarction.

Yasong Wu, Zengbao Wu, Ting Fan, Lifei Lian, Bo Chen, Zhoubin Tan, Hongquan Niu, Lin Han, Xueyan Wan

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Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yasong Wu *Department of Neurosurgery, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zengbao Wu *Department of Neurosurgery, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Ting FanDepartment of Neurosurgery, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Lifei LianDepartment of Neurology, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Bo ChenDepartment of Neurology, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zhoubin TanDepartment of Neurosurgery, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Hongquan NiuDepartment of Neurosurgery, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Lin HanDepartment of Neurosurgery, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. hanlin@tjh.tjmu.edu.cn.
Xueyan WanDepartment of Neurosurgery, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. xywan@tjh.tjmu.edu.cn.

Funding

Natural Science Foundation of Hubei Province 2021CFB394Natural Science Foundation of Hubei Province 2025AFB808the Scientific Research Starting Foundation for Returned Overseas Chinese Scholars from Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology 2020HGRY009
6 · The paper itself

Abstract

To evaluate the efficacy and safety of external ventricular drainage (EVD) in managing patients with space-occupying cerebellar infarction. The 48 patients were divided into two groups: the EVD group and the non-EVD group. The outcomes of the patient were assessed using the modified Rankin Scale (mRS), with scores of ≤ 3 indicating a favorable prognosis. Among the 48 patients, 29 underwent EVD, while 19 were in the non-EVD group. This non-EVD group included 14 patients who underwent suboccipital decompression and 5 who underwent suboccipital decompression combined with necrosectomy. In the EVD group, 20 patients had a favorable prognosis and 9 had a poor prognosis, with 6 deaths. In the non-EVD group, 16 patients had a favorable prognosis and 3 had a poor prognosis, with 3 deaths. No statistically significant differences were observed between the two groups. Multivariate logistic regression analysis revealed that a Glasgow Coma Scale (GCS) score < 9 (OR 9.5, 95% CI 1.5-77.0, P = 0.05), cerebral infarction (OR 15.6, 95% CI 2.3-144.0, P = 0.03), and the requirement for postoperative ventilatory support (OR 12.7, 95% CI 2.7-79.4, P = 0.01) were independent risk factors for poor patient outcomes. For patients with space-occupying cerebellar infarction, EVD might be an effective and safe treatment option. However, its efficacy and safety require further confirmation through prospective randomized clinical trials.

Indexed as

Brain InfarctionCerebellar DiseasesCerebellumCerebral InfarctionDrainageAdultAgedDecompression, SurgicalFemaleGlasgow Coma ScaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeEfficacyExternal ventricular drainagePrognosisSafetySpace-occupying cerebellar infarction

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.