Evidence map›Paper›PMID 41460575›Full record

ArticleDigestive diseases and sciences2026

Decreased Incidence of Acute Pancreatitis in Finland with Biliary Etiology Predominant in Initial Episodes: A Population-Based Study.

Anssi Nikkola, Jussi Nikkola, Elisa Kari, Aki Roponen, Anna Tapaninaho, Juhani Sand, Johanna Laukkarinen

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Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

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7 authors.

Anssi NikkolaDepartment of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
Jussi NikkolaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Elisa KariFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Aki RoponenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Anna TapaninahoFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Juhani SandDepartment of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
Johanna LaukkarinenDepartment of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland. johanna.laukkarinen@pirha.fi.ORCID http://orcid.org/0000-0002-8239-4861

Funding

Competitive State Research Funding of the Expert Responsibility Area of Tampere University Hospital 9U028
6 · The paper itself

Abstract

BACKGROUND AND

aimsIn the 1990s, the incidence of acute pancreatitis (AP) in Finland exceeded 70 per 100,000 inhabitants, with alcohol as the etiology in 70% of cases, whereas in most other countries biliary etiology predominates. Diagnostic methods have since improved, and more recent studies have already reported lower incidence rates and a different etiologic distribution in Finland. We report a population-based study on the current incidence and etiology of AP in Pirkanmaa Finland.

methodsAll patients treated for AP at Tampere University Hospital during 2014-2015 were identified from hospital records. Patient demographics and etiology-related data were collected.

resultsThe Pirkanmaa Hospital District population during the study period averaged 525,926. A total of 558 patients were treated for AP, comprising 622 episodes and yielding an incidence of 59.1 per 100,000 inhabitants. Of these, 451 patients (72.5%) presented with a first episode, corresponding to an incidence of 42.9 per 100,000. Among first episodes, etiology was biliary in 36.8% and alcoholic in 29.4%. For all episodes, biliary and alcoholic etiologies accounted for 32.5% and 34.1%, respectively. Other causes included post-ERCP (2.7%), tumor (3.2%), drug-induced (2.4%), autoimmune (1.4%), post-operative (1.0%), hypertriglyceridemia (0.6%), hypercalcemia (0.2%), SPINK1-associated (0.8%), miscellaneous (0.3%), idiopathic (10.6%), and not reliably determined (10.1%).

conclusionThe total incidence of AP in Pirkanmaa, Finland, was 59.1 per 100,000, and first-episode AP 42.9 per 100,000 - lower than historically reported and comparable to other Western countries. Biliary etiology was most common in first episodes, indicating that alcohol is no longer the predominant etiology of AP in the study area in Finland.

Indexed as

Biliary Tract DiseasesPancreatitisPancreatitis, AlcoholicAcute DiseaseAdolescentAdultAgedAged, 80 and overFemaleFinlandHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsAcute alcoholic pancreatitisAcute pancreatitisEtiologyFinlandIncidence

Identifiers

PMID41460575
PMCPMC13357418

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