ReviewFolia microbiologica2026
Ethyl methanesulfonate mutagenesis: Advancing bacterial genetics for sustainable agriculture.
Review in Folia microbiologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Dataset on the generation and inhibitor-based selection ofData in brief · 2026Article
- Whole-genome characterization and analysis of Pantoea agglomerans R6: a genomic insight into its pathogenicity and resistance as a potential opportunistic plant pathogen.BMC genomics · 2026Article
- Ethyl methanesulfonate mutagenesis in fungi: genetic mechanisms, applications, and implications for agricultural biotechnology.Archives of microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Ethyl methanesulfonate (EMS) is a strong alkylating agent commonly used to induce random point mutations, particularly G: C to A: T transitions, by ethylating guanine bases in DNA. Its mutagenic properties, which stem from the transfer of ethyl groups to nucleophilic sites within cells, allow for the creation of various mutant libraries, aiding research in bacterial physiology, metabolism, and antibiotic resistance. This review briefly examines the mechanisms behind EMS mutagenesis and its applications in both forward and reverse genetics. In forward genetics, mutants generated by EMS with altered traits help identify the genetic mutations responsible, while reverse genetics focuses on analyzing specific gene functions. Although there are challenges like mutation stability and reversion, advancements in high-throughput screening methods have improved the effectiveness of EMS mutagenesis. The review also emphasizes the significant impact of EMS-induced bacterial mutants in promoting sustainable agriculture and environmental management. Notable examples include the creation of non-pathogenic Ralstonia solanacearum mutants for controlling bacterial wilt, as well as Bacillus and Pseudomonas mutants that enhance biosurfactant production and bioremediation efforts. Furthermore, EMS mutagenesis has led to the development of stress-tolerant strains that can survive under drought, salinity, and heavy metal conditions, along with strains that improve phosphorus solubilization and nitrogen fixation, contributing to better soil health and plant growth. By connecting fundamental research with practical applications, EMS mutagenesis remains a vital tool for tackling global issues in agriculture, environmental sustainability, and microbial biotechnology.
Indexed as
Identifiers
41460574What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.