Evidence map›Paper›PMID 41460464›Full record

ArticleBiochemical genetics2026

Translation Initiation Fidelity Defective Mutations in eIF5 and eIF2β Show Distinct Sensitivity to the Sequence Context for Recognition of the UUG Start Codon.

Anup Kumar Ram, Tanaya Kole, Pankaj V Alone

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemical genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anup Kumar RamSchool of Biological Sciences, National Institute of Science Education and Research (NISER) Bhubaneswar, P.O. Jatni, Khurda, 752050, India.
Tanaya KoleSchool of Biological Sciences, National Institute of Science Education and Research (NISER) Bhubaneswar, P.O. Jatni, Khurda, 752050, India.
Pankaj V AloneSchool of Biological Sciences, National Institute of Science Education and Research (NISER) Bhubaneswar, P.O. Jatni, Khurda, 752050, India. pankaj@niser.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Saccharomyces cerevisiae, the AUG codon typically signals translation initiation to set an open reading frame, with a preference for the A

Indexed as

Codon, InitiatorEukaryotic Initiation Factor-2Eukaryotic Initiation Factor-2BEukaryotic Initiation Factor-5MutationPeptide Chain Initiation, TranslationalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCodon, InitiatorEukaryotic Initiation Factor-2Eukaryotic Initiation Factor-2BEukaryotic Initiation Factor-5Saccharomyces cerevisiae ProteinseIF2βeIF5Sequence contextStart codon selectionSui¯ phenotypeTranslation initiation

Identifiers

PMID41460464
PMCPMC13388412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.