Evidence map›Paper›PMID 41460326›Full record

Observational studyPediatric surgery international2025

Transanal irrigation in pediatric bowel dysfunction: a prospective study on clinical outcomes and quality of life.

Marco Di Mitri, Annalisa Di Carmine, Simone D'Antonio, Francesca Ruspi, Cristian Bisanti, Edoardo Collautti, Sara Maria Cravano, Michele Libri, Riccardo Coletta, Roberto Lo Piccolo and 3 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marco Di MitriPediatric Surgery Department, IRCCS Meyer, Florence, Italy. marcodimitri14@gmail.com.
Annalisa Di CarminePediatric Surgery Department, IRCCS Meyer, Florence, Italy.
Simone D'AntonioPediatric Surgery Department, IRCCS Sant'Orsola-Malpighi, Alma Mater Studiorum, Università degli Studi di Bologna, Bologna, Italy.
Francesca RuspiPediatric Surgery Department, IRCCS Sant'Orsola-Malpighi, Alma Mater Studiorum, Università degli Studi di Bologna, Bologna, Italy.
Cristian BisantiPediatric Surgery Department, IRCCS Meyer, Florence, Italy.
Edoardo CollauttiPediatric Surgery Department, IRCCS Meyer, Florence, Italy.
Sara Maria CravanoPediatric Surgery Department, IRCCS Meyer, Florence, Italy.
Michele LibriPediatric Surgery Department, IRCCS Sant'Orsola-Malpighi, Alma Mater Studiorum, Università degli Studi di Bologna, Bologna, Italy.
Riccardo ColettaPediatric Surgery Department, IRCCS Meyer, Florence, Italy.
Roberto Lo PiccoloPediatric Surgery Department, IRCCS Meyer, Florence, Italy.
Tommaso GarganoPediatric Surgery Department, IRCCS Sant'Orsola-Malpighi, Alma Mater Studiorum, Università degli Studi di Bologna, Bologna, Italy.
Enrico CiardiniPediatric Surgery Department, IRCCS Meyer, Florence, Italy.
Mario LimaPediatric Surgery Department, IRCCS Sant'Orsola-Malpighi, Alma Mater Studiorum, Università degli Studi di Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTransanal irrigation (TAI) is an emerging minimally invasive therapy for children with severe bowel dysfunction, including fecal incontinence and refractory constipation. The aim of this study was to evaluate the impact of TAI on bowel habits, medication use, quality of life, and caregiver burden in a pediatric population.

methodsA prospective observational study was conducted on 20 pediatric patients with fecal incontinence. A structured questionnaire assessing bowel function and quality of life was administered at baseline and after 60 days of TAI. Outcomes were compared using Fisher's exact and Wilcoxon signed-rank tests.

resultsSignificant improvements were observed in bowel care time (p < 0.01), frequency of soiling (p < 0.01), fecal incontinence episodes (p < 0.01), and dependence on laxatives or enemas (p < 0.01). Social participation and emotional well-being also improved. Most patients reported better autonomy and reduced discomfort related to bowel management.

conclusionsTAI is an effective strategy to improve continence, reduce the burden of bowel care, and enhance quality of life in children with refractory bowel dysfunction.

Indexed as

ConstipationFecal IncontinenceQuality of LifeTherapeutic IrrigationAdolescentAnal CanalChildChild, PreschoolFemaleHumansMaleProspective StudiesSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID41460326
PMCPMC12748105

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.