Evidence map›Paper›PMID 41460295›Full record

ArticleJournal of robotic surgery2025

Extraperitoneal robot-assisted radical prostatectomy with the Hugo™ RAS system: 100 consecutive cases, 1-year follow-up and surgical learning curve evaluation.

Marcello Scarcia, Giovanni Battista Filomena, Marco Montesi, Nicoletta Testori, Pierluigi Russo, Stefano Moretto, Simone Cotrufo, Francesco Paolo Maselli, Filippo Gavi, Francesco Pio Bizzarri and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Hugo™ RAS versus da VinciBMC surgery · 2026
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Marcello Scarcia *Urology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.
Giovanni Battista Filomena *Urology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy. Giovanni.filomena17@gmail.com.
Marco MontesiUrology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.
Nicoletta TestoriUrology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.
Pierluigi RussoUrology Department, Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Rome, 00168, Italy.
Stefano MorettoUrology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.
Simone CotrufoUrology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.
Francesco Paolo MaselliUrology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.
Filippo GaviUrology Department, Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Rome, 00168, Italy.
Francesco Pio BizzarriUrology Department, Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Rome, 00168, Italy.
Roberto CalbiRadiology Department, "F. Miulli" General Hospital, 70021 Acquaviva Delle Fonti, Bari, Italy.
Alba FiorentinoRadiation Oncology Department, Generale Regional Hospital F Miulli, Acquaviva Delle Fonti, 70021, Italy.
Filippo MarinoUrology Department, Humanitas Gavazzeni, Bergamo, 24121, Italy.
Maria Chiara SighinolfiUrology Department, Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Rome, 00168, Italy.
Bernardo Maria RoccoUrology Department, Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Rome, 00168, Italy.
Luigi CormioUrology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.
Giuseppe Mario LudovicoUrology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.
Michele ZazzaraUrology Department, Ospedale Generale Regionale Francesco Miulli, Acquaviva delle Fonti, 70021, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Hugo™ Robotic-Assisted Surgery (RAS) system is an emerging robotic platform; evidence on its performance for extraperitoneal robot-assisted radical prostatectomy (eRARP) remains limited. Between June 2023 and September 2024, 100 patients with prostate cancer underwent eRARP using the Hugo™ RAS system. Preoperative, intraoperative, pathological and postoperative data were collected prospectively. To assess temporal trends related to platform adoption, the cohort was divided into the first 50 and last 50 cases and learning-curve dynamics were analyzed (including CUSUM for console time). We report 12-month follow-up. Across the entire series, the median operative duration was 252.5 min (Q1-Q3 200-290), with no instances of intraoperative conversion or intraoperative complications. Major postoperative events classified as Clavien-Dindo grade III or higher were observed in 2% of patients. At the 12-month assessment, an undetectable PSA (< 0.1 ng/mL) was documented in 80% of individuals, social continence (≤ 1 pad per day) in 87%, and erectile function recovery in 51%. Overall positive surgical margin (PSM) rate was 40%, with clinically significant PSM (≥ 3 mm or multifocal) of 21%. Comparison of two groups revealed a learning effect: median operative time decreased from 275 to 210 min (p < 0.00001); docking time improved modestly (p = 0.0271). Both clinically significant PSMs (28%→14%) and overall complication rates (26%→4%, p = 0.0006) declined in the second cohort. In this prospective, single-center series, eRARP using the Hugo™ RAS system was feasible and safe. A learning-curve effect produced substantially shorter operative times and fewer complications, while oncological and functional outcomes were preserved. Longer follow-up and larger multicenter studies are needed to verify long-term equivalency with well-established robotic platforms.

Indexed as

Learning CurveProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresAgedFollow-Up StudiesHumansMaleMargins of ExcisionMiddle AgedOperative TimePostoperative ComplicationsProspective StudiesTreatment OutcomeExtraperitoneal radical prostatectomyHugo RASLearning curveProstate cancerRobotic surgerySurgical outcomes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.