SynthesisJournal of robotic surgery2025
Robot-assisted versus open partial nephrectomy in renal tumor patients with chronic kidney disease: a meta-analysis of renal functional and perioperative outcomes.
Synthesis in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The purpose of this study is to evaluate the effects of robot-assisted partial nephrectomy versus open partial nephrectomy on perioperative outcomes, complications, and glomerular filtration rate in renal tumor patients with chronic kidney disease (CKD). A comprehensive systematic review was conducted across several peer-reviewed electronic databases, such as PubMed, Cochrane Library, Embase, and Web of Science. The search encompassed publications in all languages up to October 2025. Following the exclusion of non-relevant records such as reviews and commentaries, the eligible studies were subjected to meta-analysis. This was performed using Review Manager, employing weighted mean differences (WMD) and odds ratios (OR) for the evaluation of continuous and dichotomous variables, respectively. The review protocol was registered with PROSPERO (CRD No. 420251207798). Pooled data from 868 patients across three retrospective cohort studies revealed that RAPN offers a favorable profile compared to OPN for patients with renal tumors and chronic renal insufficiency. The benefits of RAPN included minimized blood loss (MD -148.8, 95% CI [-235.61, -62.16]; p = 0.0008), reduced hospitalization duration (MD -2.73, 95% CI [-4.24, -1.23]; p = 0.0004), and superior postoperative glomerular filtration rate recovery (MD 1.77, 95% CI [1.37, 2.18]; p < 0.00001). Conversely, no statistically significant differences were identified for other evaluated parameters, including operative time, transfusion rate, complication incidence, ischemia time, or positive surgical margins. In conclusion, this meta-analysis of three retrospective studies suggests that robotic-assisted surgery holds promise as a preferable treatment strategy. However, the strength of this conclusion is limited by the small number of studies, their retrospective design, and notable clinical heterogeneity (e.g., in baseline renal function). To definitively establish these benefits, confirmation from future large-scale, high-quality randomized controlled trials is necessary.
Indexed as
Identifiers
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Registered trials
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