Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia.
Naidi Sun, Yu-Yo Sun, Rui Cao, Hong-Ru Chen, Yiming Wang, Elizabeth Fugate, Marchelle R Smucker, Yi-Min Kuo, Ellen P Grant, Diana M Lindquist and 2 more
Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Integrating TPM and PAM to examine the metabolic underpinning of neurovascular repair after strokeR01NS120481 · NINDS · WASHINGTON UNIVERSITY · PI HU, SONG, LEE, JIN-MOO · 2021 to 2025
$3.1M
CMRO2 and Uncoupling of Oxidative-Phosphorylation in Experimental HIER01NS125677 · NINDS · UNIVERSITY OF VIRGINIA · PI Song Hu, Chia-Yi Kuan · 2022 to 2026
$2.8M
Treating neurotoxicity and cognitive deficits due to hyperphosphorylated tau.R01NS135693 · NINDS · UNIVERSITY OF VIRGINIA · PI Chia-Yi Kuan, Min-Hao Kuo · 2023 to 2026
$2.4M
Neutrophils and Monocytes in Pediatric Ischemic StrokeR01NS125788 · NINDS · UNIVERSITY OF VIRGINIA · PI Chia-Yi Kuan · 2022 to 2026
$2.1M
Photoacoustic Microscopy of the Awake Mouse BrainR01NS099261 · NINDS · WASHINGTON UNIVERSITY · PI HU, SONG · 2017 to 2021
$1.7M
Monocyte-Derived Microglia in Development and after Neonatal Brain InjuryR21HD109025 · NICHD · UNIVERSITY OF VIRGINIA · PI KUAN, CHIA-YI · 2023 to 2024
$444k
Perivascular Fibroblast-Endothelium Interactions in Hypertension and Cerebral IschemiaR21NS127392 · NINDS · UNIVERSITY OF VIRGINIA · PI KUAN, CHIA-YI · 2022 to 2023
$444k
National Science and Technology Council MOST 111-2320-B-110-003-MY2National Science and Technology Council NSTC 113-2320-B110-010National Science Foundation NSF CAREER 202988NICHD NIH HHS R21 HD109025NIH HHS HD109025NIH HHS NS099261NIH HHS NS120481NIH HHS NS125677NIH HHS NS125788NIH HHS NS127392NINDS NIH HHS R01 NS099261NINDS NIH HHS R01 NS120481NINDS NIH HHS R01 NS125677NINDS NIH HHS R01 NS125788NINDS NIH HHS R01 NS135693NINDS NIH HHS R21 NS127392
6 · The paper itself
Abstract
Hypoxia-ischemia (HI), which disrupts the oxygen supply-demand balance in the brain by impairing blood oxygen supply and the cerebral metabolic rate of oxygen (CMRO
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia. · full record | OpenQuestion