Evidence map›Paper›PMID 41460182›Full record

ArticleBioinformatics (Oxford, England)2026

ViMOP: a user-friendly and field-applicable pipeline for untargeted viral genome nanopore sequencing.

Nils Peter Petersen, Mia Le, Annick Renevey, Ehizojie Emua, Sarah Ryter, Giuditta Annibaldis, Jacob Camara, Sanaba Boumbaly, Cyril Erameh, Tanja Laske and 5 more

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nosocomial Outbreak of Lassa Fever in Conakry, Guinea, 2022.The Journal of infectious diseases · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nils Peter PetersenBernhard Nocht Institute for Tropical Medicine (BNITM), 20359 Hamburg, Germany.ORCID 0000-0002-0557-3567
Mia LeBernhard Nocht Institute for Tropical Medicine (BNITM), 20359 Hamburg, Germany.ORCID 0009-0006-7677-5306
Annick ReneveyBernhard Nocht Institute for Tropical Medicine (BNITM), 20359 Hamburg, Germany.ORCID 0000-0001-7411-6063
Ehizojie EmuaViral and Emergent Pathogens Control and Research, Irrua Specialist Teaching Hospital, 310115 Irrua, Edo State, Nigeria.ORCID 0009-0004-9968-0815
Sarah RyterBernhard Nocht Institute for Tropical Medicine (BNITM), 20359 Hamburg, Germany.ORCID 0000-0003-1597-9656
Giuditta AnnibaldisBernhard Nocht Institute for Tropical Medicine (BNITM), 20359 Hamburg, Germany.ORCID 0009-0007-1570-4624
Jacob CamaraVirology Research Center/Laboratory of Viral Hemorrhagic Fevers, 001 Conakry, Guinea.ORCID 0000-0003-4837-0206
Sanaba BoumbalyVirology Research Center/Laboratory of Viral Hemorrhagic Fevers, 001 Conakry, Guinea.ORCID 0000-0002-4506-6033
Cyril EramehViral and Emergent Pathogens Control and Research, Irrua Specialist Teaching Hospital, 310115 Irrua, Edo State, Nigeria.ORCID 0000-0001-7783-2495
Tanja LaskeInstitute for Computational Systems Biomedicine, University of Hamburg, 22761 Hamburg, Germany.ORCID 0000-0002-7922-7595
Jan BaumbachInstitute for Computational Systems Biomedicine, University of Hamburg, 22761 Hamburg, Germany.ORCID 0000-0002-0282-0462
Philippe LemeyDepartment of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute, 3000 Leuven, Belgium.ORCID 0000-0003-2826-5353
Stephan GüntherBernhard Nocht Institute for Tropical Medicine (BNITM), 20359 Hamburg, Germany.ORCID 0000-0002-6562-0230
Sophie DuraffourBernhard Nocht Institute for Tropical Medicine (BNITM), 20359 Hamburg, Germany.ORCID 0000-0002-1239-4372
Liana Eleni KafetzopoulouBernhard Nocht Institute for Tropical Medicine (BNITM), 20359 Hamburg, Germany.ORCID 0000-0003-4531-1374

Funding

BWFGB Hamburg and the Leibniz Association W75/2022COVID-19 surge fund ZMVI1-2520COR001DZIFEuropean Union through the Civil Protection Pool Upgrade or Repair of Response Capacities ECHO/PREP/INT/SUB/2022/883987/Adaptation/DE/EmLabEuropean Union through the Civil Protection Pool Upgrade or Repair of Response Capacities UCPM-2022-ECPP-URCFederal Ministry of Education and Research (BMBF)German Center for Infection ResearchGerman Federal Ministry of HealthGlobal Health Protection Program ZMI1-2521GHP921Global Health Protection Program ZMI5-2523GHP006Global Health Protection Program ZMI5-2523GHP008Global Health Protection Program ZMV I1-2517GHP-704Global Health Protection Program ZMVI1-2519GHP704Leibniz ScienceCampus InterACtResearch and Innovation Program of the European Union under H2020Research Foundation-Flanders 12X9222NResearch Foundation-Flanders G005323NResearch Foundation-Flanders G051322NUniversität Hamburg with funds of the Excellence Strategy of the Federal GovernmentWHO Collaborating Centre for Arboviruses and Hemorrhagic Fever Viruses at the Bernhard-Nocht-Institute for Tropical Medicine ZMV I1-2517WHO005
6 · The paper itself

Abstract

motivationUntargeted, also known as metagenomic, nanopore sequencing is a powerful tool for virus genomic surveillance, particularly in resource-limited settings and when paired with the portability of the MinION device (Oxford Nanopore Technologies, ONT). However, a major bottleneck for global access is the absence of a user-friendly software capable of efficiently analyzing untargeted nanopore sequencing data to generate high-quality consensus genomes.

resultsWe share ViMOP, a pipeline built on our long-term experience in nanopore field sequencing. The pipeline emphasizes field user-friendliness, flexibility and versatility to analyze reads generated directly from human clinical samples. The software assembles de novo contigs, matches contigs to known viral references and uses them to assemble consensus genomes. Executed with a single Nextflow command or via the EPI2ME Desktop interface (ONT), results are summarized in an HTML report. ViMOP, through its user-centered design, lowers the barrier to high-quality virus genome reconstruction and advances capacity for genomic surveillance. AVAILABILITY AND IMPLEMENTATION: ViMOP is freely available for non-commercial use (https://github.com/opr-group-bnitm/vimop and https://zenodo.org/records/17913089), along with the associated database (https://zenodo.org/records/17652512), the scripts used to generate it (https://zenodo.org/records/17632662) and benchmarking code (https://zenodo.org/records/17633185).

Indexed as

Genome, ViralNanopore SequencingSequence Analysis, DNASoftwareHumansMetagenomicsNanopores

Identifiers

PMID41460182
PMCPMC12809542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.