Evidence map›Paper›PMID 41460168›Full record

ArticleeLife2025

A system for functional studies of the major virulence factor of malaria parasites.

Jakob Cronshagen, Johannes Allweier, Joëlle Paolo Mesén-Ramírez, Jan Stäcker, Anna Viktoria Vaaben, Gala Ramón-Zamorano, Isabel Naranjo-Prado, Max Graser, Patricia López-Barona, Susann Ofori and 10 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. ThemSphere · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jakob CronshagenPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.ORCID https://orcid.org/0000-0002-4879-8053
Johannes AllweierInterface section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.ORCID https://orcid.org/0000-0002-5845-5804
Joëlle Paolo Mesén-RamírezPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Jan StäckerPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Anna Viktoria VaabenCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen, Denmark.
Gala Ramón-ZamoranoPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Isabel Naranjo-PradoPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Max GraserPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.ORCID https://orcid.org/0009-0003-1990-4712
Patricia López-BaronaPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.ORCID https://orcid.org/0000-0002-2691-5263
Susann OforiInterface section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Pascal W T C JansenDepartment of Molecular Biology, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University, Nijmegen, Netherlands.
Joëlle HornebeckPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Florian KieferleInterface section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Agnes MurkInterface section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Elicia MartinCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen, Denmark.
Carolina Castro-PeñaPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.ORCID https://orcid.org/0000-0002-6878-4951
Richárd BártfaiDepartment of Molecular Biology, Faculty of Science, Radboud University, Nijmegen, Netherlands.
Thomas LavstsenCentre for translational Medicine & Parasitology, Department of Immunology and Microbiology, University of Copenhagen and Department of Infectious Diseases, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-3044-4249
Iris BruchhausInterface section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.ORCID https://orcid.org/0000-0002-3363-7409
Tobias SpielmannPathogen section, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.ORCID https://orcid.org/0000-0002-3968-4601

Funding

Deutsche Forschungsgemeinschaft 1744/17-1Deutsche Forschungsgemeinschaft SP1209/4-1European Research Council grant agreement No. 101021493Independent Research Fund Denmark 9039-00285ALeibniz Collaborative Excellence K328/2020Lundbeck Foundation R344-2020-934
6 · The paper itself

Abstract

PfEMP1 is a variable antigen displayed on erythrocytes infected with the malaria parasite

Indexed as

Plasmodium falciparumProtozoan ProteinsVirulence FactorsErythrocytesHumansMalaria, Falciparumerythrocyte membrane protein 1, Plasmodium falciparumProtozoan ProteinsVirulence FactorsBioIDinfectious diseasemalariamicrobiologyP. falciparumPfEMP1protein exportselection linked integrationvirluence

Identifiers

PMID41460168
PMCPMC12747541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.