Observational studyIndian journal of ophthalmology2026
Associations between ocular surface parameters, contrast sensitivity, and higher-order aberrations in computer vision syndrome.
Observational study in Indian journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate changes in ocular surface parameters, contrast sensitivity (CS), and higher-order aberrations (HOAs) in patients with computer vision syndrome (CVS)/digital eye strain (DES), and to assess associations among these factors.
designProspective observational case-control study.
methodsBoth eyes of 55 CVS cases (CVS-Q score ≥ 6) and 55 age-matched controls (18-40 years) with best-corrected visual acuity (BCVA) of 6/6 were enrolled. Participants with ocular comorbidities were excluded. Central and peripheral CS were assessed using the Pelli-Robson (PR) chart and Spaeth-Richman contrast sensitivity test (SPARCS). Dry eye disease (DED) workup was performed. HOAs were measured using a wavefront aberrometer (iDesign® Refractive Studio, Johnson and Johnson Surgical Vision, Inc.).
resultsPR scores were identical across groups. SPARCS revealed significantly reduced total CS scores (central and peripheral) in the CVS group (W = 3641.000, P < 0.001), highlighting its sensitivity to subtle CS changes. The CVS group showed significantly higher HOA values (%), root mean square HOA error (P < 0.001), and spherical aberration (P = 0.033), along with more severe DED findings.
conclusionCVS/DES leads to impaired visual function due to reduced CS, increased HOAs, and dry eye. Assessment of both central and peripheral CS provides a more complete understanding of its impact on visual quality and daily functioning. Early ergonomic interventions and preventive strategies are vital for protecting ocular health in an increasingly digital world.
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