Evidence map›Paper›PMID 41460130›Full record

Trial reportIndian journal of ophthalmology2026

Outcomes of pediatric cataract surgery: Intraoperative triamcinolone injection versus dexamethasone injection.

Srishti Agarwal, Parul Chawla Gupta, Muhammad Aaqib Shamim, Ranjan Kumar Behera, Jaspreet Sukhija, Shweta Chaurasia, Savleen Kaur, Surinder Singh Pandav, Jagat Ram, Sanjay Verma

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Indian journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Srishti AgarwalDepartment of Ophthalmology, Advanced Eye Centre, PGIMER, Chandigarh, India.
Parul Chawla GuptaDepartment of Ophthalmology, Advanced Eye Centre, PGIMER, Chandigarh, India.
Muhammad Aaqib ShamimDepartment of Pharmacology, AIIMS, Jodhpur, Rajasthan, India.
Ranjan Kumar BeheraDepartment of Ophthalmology, Advanced Eye Centre, PGIMER, Chandigarh, India.
Jaspreet SukhijaDepartment of Ophthalmology, Advanced Eye Centre, PGIMER, Chandigarh, India.
Shweta ChaurasiaDepartment of Ophthalmology, Advanced Eye Centre, PGIMER, Chandigarh, India.
Savleen KaurDepartment of Ophthalmology, Advanced Eye Centre, PGIMER, Chandigarh, India.
Surinder Singh PandavDepartment of Ophthalmology, Advanced Eye Centre, PGIMER, Chandigarh, India.
Jagat RamDepartment of Ophthalmology, Grewal Eye Institute, Chandigarh, India.
Sanjay VermaDepartment of Pediatrics, Advanced Pediatrics Centre, PGIMER, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the clinical outcomes of cataract surgery by injecting intracameral triamcinolone or dexamethasone in children with bilateral congenital or developmental cataracts.

designProspective, interventional, assessor-blinded, randomized controlled trial.

methodsThis was an institutional study in which 24 children aged <6 years with congenital/developmental cataracts were randomly divided into two groups. Eyes with other associated ocular conditions were excluded. Intracameral triamcinolone acetonide 1.2 mg/0.03 ml in the control group and dexamethasone 0.4 mg/0.1 ml in the study group were injected at the end of cataract surgery. The primary aim was to compare the number of eyes requiring surgery and postoperative outcomes such as anterior segment inflammation, intraocular lens pigment deposition, and posterior synechiae.

resultsThe mean age was 20.04 months ± 17.88 (SD) (range 6 to 72 months) out of the 24 children being studied. One eye in the control group and three eyes in the study group required synechiolysis, membranectomy, and dialing of the intraocular lens with no statistically significant difference between the two groups (P = 0.60). The median intraocular pressure and central corneal thickness did not change significantly postoperatively in either group. Both groups showed similar cellular reactions and rate of complications.

conclusionsIntracameral dexamethasone can be used as an effective alternative to intracameral triamcinolone for modulating postoperative anterior segment inflammation in pediatric cataract surgery. This pilot study compares the safety and efficacy of two drugs used in pediatric cataract surgery, despite limitations such as a small sample size and a short follow-up period.

Indexed as

CataractCataract ExtractionDexamethasoneTriamcinolone AcetonideVisual AcuityChildChild, PreschoolFemaleFollow-Up StudiesGlucocorticoidsHumansInfantInjections, IntraocularIntraoperative CareMaleProspective StudiesDexamethasoneGlucocorticoidsTriamcinolone AcetonideChildhood cataract surgeryintracameral steroidspediatric cataract

Identifiers

PMID41460130
PMCPMC12867298

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.