Evidence map›Paper›PMID 41459996›Full record

ReviewThe journal of pathology. Clinical research2026

Implementing Immunoscore in colorectal cancer: lessons from cohort studies, limitations and barriers to adoption.

Matthew Ss Hsu, Suet Yi Leung

Abstract readReview
In one paragraph

Review in The journal of pathology. Clinical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew Ss HsuDepartment of Pathology, School of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong.ORCID 0009-0006-2282-1725
Suet Yi LeungDepartment of Pathology, School of Clinical Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong.ORCID 0000-0001-8614-4619

Funding

the Centre for Oncology and Immunology under the Health@InnoHK Initiative funded by the Innovation and Technology Commission, The Government of Hong Kong SAR, China
6 · The paper itself

Abstract

The Immunoscore (IS) quantifies the immune contexture of colorectal cancer (CRC) by measuring CD3

Indexed as

Biomarkers, TumorColorectal NeoplasmsLymphocytes, Tumor-InfiltratingChemotherapy, AdjuvantCohort StudiesHumansImmune Checkpoint InhibitorsNeoplasm StagingPrognosisBiomarkers, TumorImmune Checkpoint Inhibitorscoloncolon cancerdigital image analysisdigital pathologyimmunohistochemistryimmunologyImmunoscore

Identifiers

PMID41459996
PMCPMC12746701

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.