Evidence map›Paper›PMID 41459942›Full record

ArticleJournal of bacteriology2026

The roles of the

Jada L George, Leah F Cabo, Jon P Boyle, Nancy E Freitag, Laty A Cahoon

Abstract read
In one paragraph

Article in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jada L GeorgeDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Leah F CaboDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jon P BoyleDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0000-9243
Nancy E FreitagDepartment of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID 0000-0003-1322-3978
Laty A CahoonDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2061-319X

Funding

Post-translation regulation of Listeria monocytogenes virulence factorsR01AI083241 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FREITAG, NANCY ELIZABETH · 2011 to 2019
$3.5M
Interinstitutional Program in Cell and Molecular Biology: A Graduate Training Path to Promote Traditional and Non-Traditional Professional OutcomesT32GM133353 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRODSKY, JEFFREY L., MURRAY, SANDRA ANN · 2020 to 2024
$1.5M
Gram-positive secretion chaperone-client interactionsR35GM159731 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Laty Adriella Cahoon · 2025 to 2026
$804k
Characterization of pneumococcal secretion chaperones required for virulenceR00AI128029 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAHOON, LATY ADRIELLA · 2020 to 2021
$474k
Characterization of pneumococcal secretion chaperones required for virulenceK99AI128029 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CAHOON, LATY ADRIELLA · 2017 to 2018
$251k
NIAID NIH HHS K99 AI128029NIAID NIH HHS R00 AI128029NIAID NIH HHS R01 AI083241NIGMS NIH HHS R35 GM159731NIGMS NIH HHS T32 GM133353NIH HHS K99/R00 AI128029NIH HHS R01AI083241NIH HHS R35GM159731NIH HHS T32GM133353
6 · The paper itself

Abstract

PrsA1 and PrsA2 are parvulin peptidyl-prolyl isomerases that function as post-translocation secretion chaperones in IMPORTANCE: Bacterial protein secretion is critical for functions ranging from cell physiology to virulence. Here, we examine the effect of deleting two

Indexed as

Bacterial ProteinsListeria monocytogenesMolecular ChaperonesPeptidylprolyl IsomeraseStress, PhysiologicalGene DeletionGene Expression Regulation, BacterialLipoproteinsMembrane ProteinsProtein TransportBacterial ProteinsLipoproteinsMembrane ProteinsMolecular ChaperonesPeptidylprolyl IsomerasePrsA2 protein, Listeria monocytogenesprsA protein, bacteriachaperonegram-positive secretionListeria monocytogenesparvulinPPIasePrsA1PrsA2secretomestress resistance

Identifiers

PMID41459942
PMCPMC12826049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.