ArticleJournal of medical virology2026
Arrival of Oropouche Virus in a Nonendemic Area in Northeastern Brazil, 2024.
Article in Journal of medical virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Arrival of Oropouche Virus in a Nonendemic Area in Northeastern Brazil, 2024.Journal of medical virology · 2026Article
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Authors and funding
15 authors.
Funding
Abstract
Orthobunyavirus oropoucheense (OROV) causes Oropouche fever, which exhibits symptoms similar to those of other arboviral diseases. Although it has historically been restricted to the Amazon region, the virus has recently spread to other areas of Brazil. Alagoas state, with low socioeconomic conditions and limited health coverage, has seen an increase in febrile cases without confirmed molecular diagnoses of circulating arboviruses. By September 6, 2024, 1316 samples negative for Dengue, Zika, and Chikungunya were tested for OROV and Mayaro virus using RT-qPCR, yielding 115 (8.74%) positive results for OROV. Among these, 14 (22.22%) viral isolates were obtained in Vero cells and confirmed by RT-qPCR and immunofluorescence assay (IFA). The study generated 37 new near-complete genomic sequences corresponding to the newly characterized OROV lineage and examined selection pressures on the M gene, identifying sites under purifying selection. We identified amino acid variations in the Gc glycoprotein structure at positions 507, 552, 738, and 795, which may influence host-cell interactions. This work is the first to report OROV in Alagoas, emphasizing the need for improved monitoring and control measures to mitigate public health impacts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.