Evidence map›Paper›PMID 41459530›Full record

ArticleFrontiers in immunology2025

Mitochondrial calcium shapes B cell signaling and mitochondrial function.

Hakan Taskiran, Elena Czeslik, Leonhard Stark, Kathrin Kläsener, Theresa Elisa Schnalzger, Jürgen Ruland, Michael Reth, Julia Jellusova

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hakan TaskiranInstitute of Clinical Chemistry and Pathobiochemistry, School of Medicine and Health, University Hospital of Technical University of Munich, Munich, Germany.
Elena CzeslikInstitute of Clinical Chemistry and Pathobiochemistry, School of Medicine and Health, University Hospital of Technical University of Munich, Munich, Germany.
Leonhard StarkTranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany.
Kathrin KläsenerDepartment of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Centre for Biological Signalling Studies and Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.
Theresa Elisa SchnalzgerInstitute of Clinical Chemistry and Pathobiochemistry, School of Medicine and Health, University Hospital of Technical University of Munich, Munich, Germany.
Jürgen RulandInstitute of Clinical Chemistry and Pathobiochemistry, School of Medicine and Health, University Hospital of Technical University of Munich, Munich, Germany.
Michael RethDepartment of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Centre for Biological Signalling Studies and Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.
Julia JellusovaInstitute of Clinical Chemistry and Pathobiochemistry, School of Medicine and Health, University Hospital of Technical University of Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Calcium (Ca Methods: Chemical dyes as well as a genetically encoded Ca Results: Here, we show that mitochondrial Ca Discussion: The spatial and temporal dynamics of Ca

Indexed as

B-LymphocytesCalciumCalcium SignalingMitochondriaAnimalsCalcium ChannelsCell Line, TumorEndoplasmic ReticulumHumansLymphocyte ActivationMiceMice, Inbred C57BLReceptors, Antigen, B-CellSignal TransductionCalciumCalcium Channelsmitochondrial calcium uniporterReceptors, Antigen, B-CellB lymphocytecalciummetabolismmitochondriasignaling

Identifiers

PMID41459530
PMCPMC12738928

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.