Evidence map›Paper›PMID 41459401›Full record

ArticleFrontiers in nuclear medicine2025

Comparative dosimetric evaluation of 68Ga-PSMA and 18F-Choline PET/CT imaging in prostate cancer: implications for radiation safety and SUVmax correlation.

Hussein R Kaafarani, Mohamad Haidar, Hanna El-Balaa

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Article in Frontiers in nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hussein R KaafaraniDepartment of Nuclear Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Mohamad HaidarDepartment of Nuclear Medicine, American University of Beirut (AUB), Beirut, Lebanon.
Hanna El-BalaaMedical Physics (Beirut/Hadath), Lebanese University, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Comparative patient dosimetry for diagnostic PET/CT can guide radiation-safety procedures and tracer selection in prostate cancer. We compared [^68Ga]Ga-PSMA-11 and ^18F-choline PET/CT and examined whether kidney SUVmax predicts patient effective dose (ED). Methods: Prospective single-center study of consecutive men undergoing clinically indicated PET/CT: 70 ^68Ga-PSMA-11 and 70 ^18F-choline examinations (Jan 2022-Dec 2023). Dose-rate measurements were recorded at the injection site and at 1 m, immediately post-injection and at 1 h. ED was derived from literature-based tracer coefficients (h_PSMA-11 = 0.0169 mSv/MBq; h_F-choline = 0.0173 mSv/MBq). Kidney SUVmax was extracted in a subset ( Results: Mean surface dose rate was higher with ^68Ga-PSMA vs. ^18F-choline (4.9 ± 0.8 vs. 4.5 ± 0.7 µSv·h Conclusions: ^68Ga-PSMA yields slightly higher dose-rate readings than ^18F-choline, while overall ED is comparable. These exploratory correlations do not support SUVmax as a stand-alone safety surrogate or outcome predictor.

Indexed as

^18F-Choline^68Ga-PSMAdosimetryPET/CTprostate cancerradiation safetySUVmax

Identifiers

PMID41459401
PMCPMC12741963

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