Evidence map›Paper›PMID 41459376›Full record

ArticleSynlett : accounts and rapid communications in synthetic organic chemistry2021

Collaboration in Natural Product Total Synthesis: Carolacton - A Decade of Discovery.

Amy E Solinski, William M Wuest

Abstract read
In one paragraph

Article in Synlett : accounts and rapid communications in synthetic organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amy E SolinskiDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, USA.
William M WuestDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, USA.ORCID 0000-0002-5198-7744

Funding

Tool Compounds to Probe Multispecies Biofilms in the Human Oral MicrobiomeR01DE025837 · NIDCR · TEMPLE UNIV OF THE COMMONWEALTH · PI WUEST, WILLIAM M · 2016 to 2020
$1.8M
NIDCR NIH HHS R01 DE025837
6 · The paper itself

Abstract

Carolacton, a macrocyclic natural product with impressive anti-biofilm biological activity, has been a focus in multiple research groups for the past decade. Chemists and biologists, alike, have been interested in uncovering the mechanism of action and have made great strides towards this goal. Carolacton causes cellular defects in

Indexed as

antibioticsbiofilmscarolactondiverted total synthesisnatural products

Identifiers

PMID41459376
PMCPMC12742669

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.