Evidence map›Paper›PMID 41459368›Full record

ArticleCase reports in dentistry2025

Clinical Pharmacist's Role in Preventing and Managing Drug-Induced Oral Ulceration: A Bisphosphonate Case in an Older Adult Care Setting.

Motohiko Sano, Yosuke Iijima, Miki Yamada, Shunsuke Hino, Maho Shinogi, Norio Horie, Takahiro Kaneko

Abstract read
In one paragraph

Article in Case reports in dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Motohiko SanoLaboratory of Clinical Pharmacy Assessment, Hoshi University, Tokyo, Japan, hoshi.ac.jp.ORCID https://orcid.org/0000-0001-8714-8101
Yosuke IijimaDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan, saitama-med.ac.jp.ORCID https://orcid.org/0000-0002-3804-6122
Miki YamadaDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan, saitama-med.ac.jp.ORCID https://orcid.org/0000-0002-7980-5156
Shunsuke HinoDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan, saitama-med.ac.jp.ORCID https://orcid.org/0000-0002-9690-1713
Maho ShinogiLaboratory of Clinical Pharmacy Assessment, Hoshi University, Tokyo, Japan, hoshi.ac.jp.
Norio HorieDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan, saitama-med.ac.jp.
Takahiro KanekoDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan, saitama-med.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphosphonate-induced oral mucosal ulcers are rare adverse events distinct from medication-related osteonecrosis of the jaw. This case demonstrates successful conservative management through the modification of drug administration in an older adult care facility. A 91-year-old woman with dementia developed bilateral floor of the mouth and sublingual ulceration that persisted for 2 weeks. Histopathological examination excluded malignancy and confirmed a drug-induced etiology. Management involved correcting the minodronic acid administration technique without discontinuing therapy, which resulted in complete resolution within 4 weeks. This case underscores the importance of appropriate medication administration education and pharmacist involvement in the care of older adults to prevent and manage drug-related oral diseases.

Indexed as

adverse eventbisphosphonateolder adult careoral ulcerpharmacist intervention

Identifiers

PMID41459368
PMCPMC12740646

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.