Evidence map›Paper›PMID 41459304›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2025

A simulation study of fluorescein attenuation and dynamic tracer kinetic model-extracted retinal blood flow from human retinal fluorescein videoangiographies.

Sarah R Vavrek, Elif Kayaalp Nalbant, Nicholas Konopek, Nicole L Decker, Amani A Fawzi, William F Mieler, Jennifer J Kang-Mieler, Kenneth M Tichauer

Abstract read
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In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah R VavrekDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA 60616.
Elif Kayaalp NalbantDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA 60616.
Nicholas KonopekDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA 60611.
Nicole L DeckerDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA 60611.
Amani A FawziDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA 60611.
William F MielerDepartment of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, USA 60607.
Jennifer J Kang-MielerDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ, USA 07030.
Kenneth M TichauerDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA 60616.

Funding

Dynamic Tracer Kinetic Model to Detect Preclinical Diabetic Retinopathy (DR)R01EY032222 · NEI · THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY · PI KANG-MIELER, JENNIFER J · 2021 to 2025
$2.4M
NEI NIH HHS R01 EY032222
6 · The paper itself

Abstract

Diabetes mellitus catalyzes blood-retinal barrier degeneration and alterations to retinal hemodynamics, leading to changes in retinal vascular permeability and retinal blood flow

Indexed as

Beer-Lambert Lawdiabetic retinopathyfluorescein attenuationfluorescein videoangiographieskinetic modelingpreclinical biomarkerRetinal blood flowretinal vascular permeability

Identifiers

PMID41459304
PMCPMC12742667

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.