ArticleCytoJournal2025
Prominent repair-like changes that mimic atypical squamous cells after radiation treatment in the lung: A report of two cases.
Article in CytoJournal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Radiation changes in lung cytology specimens can lead to diagnostic challenges, especially during on-site evaluation. We present a case of two patients, both with a prior history of lung malignancy and subsequent radiation treatment, one with a metastatic high-grade undifferentiated pleomorphic sarcoma and the other with a small cell carcinoma. One was thought to be malignant, and one was thought to be atypical on-site. Common to both cases was a hypocellularity and a prominent repair-like/reactive change with polygonal cells or elongated fiber-like cells and dense cytoplasm mimicking atypical squamous cells in shape and cytoplasm. Knowledge of these prominent findings may help cytopathologists quickly recognize radiation changes at on-site evaluation and avoid overcalls.
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