ReviewJournal of clinical and experimental dentistry2025
Influence of age and sex on platelet count: Implications for optimizing growth factor-rich plasma preparation.
Review in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Physiological predictors of hematological tier outcomes in canine platelet-rich plasma: a prospective observational study.Frontiers in veterinary science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Growth factor-rich plasma (GFRP) is a biomedical procedure used to promote tissue regeneration. Platelet-rich plasma (PRP) contains higher-than-average platelet concentrations and includes platelet-derived growth factors. As an autologous blood derivative, it is widely used to enhance healing and tissue regeneration . In dentistry, GFRP accelerates soft tissue healing and bone regeneration in procedures such as complex extractions, bone grafts, cyst treatments, and to improve dental implant osseointegration. Objective: To assess the potential influence of age and sex on platelet count, with the aim of optimizing the standardization of therapies involving growth factors. Material and Methods: A cross-sectional, observational, and comparative study was conducted, including a total of 384 patients. Participants were stratified into six groups based on age. From their medical records, the platelet counts obtained from analyses meeting the established inclusion criteria were recorded. Subsequently, the distribution of platelet levels was analyzed according to age groups and sex. Additionally, the potential correlation between platelet count and age was evaluated. Results: The mean platelet count was higher in women (260.9 ± 65.9 x10³/µL) than in men (250.4 ± 62.0 x10³/µL), although the difference was not statistically significant (p = 0.113). A statistically significant negative correlation was found between age and platelet count (r = -0.175; p < 0.01), indicating that platelet count decreases with age, although the correlation coefficient was low. Conclusions: Platelet count varies across the population; therefore, blood extraction for PRP preparation should be adjusted based on age group and sex.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.